38076-76-5 Usage
Uses
Used in Pharmaceutical Industry:
6-Chloro-2-hydroxynicotinic acid is used as a precursor in the synthesis of pharmaceuticals for its unique chemical properties, contributing to the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, 6-Chloro-2-hydroxynicotinic acid is utilized as a starting material for the production of agrochemicals, such as pesticides and herbicides, due to its potential to enhance the effectiveness of these products.
Used in Fine Chemicals Industry:
6-Chloro-2-hydroxynicotinic acid is employed as a building block in the production of fine chemicals, where its unique structure allows for the creation of a variety of specialized chemical compounds for various applications.
Used in Organic Chemistry Research:
6-Chloro-2-hydroxynicotinic acid is used as a research compound in the field of organic chemistry, where its potential as a building block for the synthesis of diverse chemical compounds is explored.
Used in Antimicrobial and Anti-fungal Applications:
6-Chloro-2-hydroxynicotinic acid has been studied for its biological activities, including its potential antimicrobial and antifungal properties, making it a candidate for use in applications requiring these characteristics, such as in sanitizing products or in the development of new antimicrobial agents.
Check Digit Verification of cas no
The CAS Registry Mumber 38076-76-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,8,0,7 and 6 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 38076-76:
(7*3)+(6*8)+(5*0)+(4*7)+(3*6)+(2*7)+(1*6)=135
135 % 10 = 5
So 38076-76-5 is a valid CAS Registry Number.
38076-76-5Relevant academic research and scientific papers
A tautomeric ligand enables directed C-H hydroxylation with molecular oxygen
Li, Zhen,Wang, Zhen,Chekshin, Nikita,Qian, Shaoqun,Qiao, Jennifer X.,Cheng, Peter T.,Yeung, Kap-Sun,Ewing, William R.,Yu, Jin-Quan
, p. 1452 - 1457 (2021/06/30)
Hydroxylation of aryl carbon-hydrogen bonds with transition metal catalysts has proven challenging when oxygen is used as the oxidant. Here, we report a palladium complex bearing a bidentate pyridine/ pyridone ligand that efficiently catalyzes this reaction at ring positions adjacent to carboxylic acids. Infrared, x-ray, and computational analysis support a possible role of ligand tautomerization from monoanionic (L,X) to neutral (L,L) coordination in the catalytic cycle of aerobic carbon-hydrogen hydroxylation reaction. The conventional site selectivity dictated by heterocycles is overturned by this catalyst, thus allowing late-stage modification of compounds of pharmaceutical interest at previously inaccessible sites.
Rhodium-Catalyzed C4-Selective C-H Alkenylation of 2-Pyridones by Traceless Directing Group Strategy
Hazra, Sunit,Hirano, Koji,Miura, Masahiro
supporting information, p. 1388 - 1393 (2021/03/03)
A rhodium-catalyzed C4-selective C-H alkenylation of 3-carboxy-2-pyridones with styrenes has been developed. The carboxylic group at the C3 position works as the traceless directing group, and the corresponding C4-alkenylated 2-pyridones are obtained exclusively with concomitant decarboxylation. Unlike the reported procedures, the exclusive C4 selectivity is uniformly observed even in the presence of potentially more reactive C-H bonds at the C5 and C6 positions. By using this strategy, the multiply substituted 2-pyridone can be prepared via sequential C-H functionalization reactions.
