3808-42-2

Basic information

• Product Name: streptothricin F
• Synonyms: streptothricin F;(3aS)-2-[[4-O-(Aminocarbonyl)-2-[[(S)-3,6-diamino-1-oxohexyl]amino]-2-deoxy-β-D-gulopyranosyl]amino]-1,3aβ,5,6,7,7aα-hexahydro-7β-hydroxy-4H-imidazo[4,5-c]pyridin-4-one;Antibiotic S-15-1A;Racemomycin A;Streptothricin VI;Yazumycin A
• CAS NO: 3808-42-2
• Molecular Formula: C19H34N8O8
• Molecular Weight: 502.526
• Mol File: 3808-42-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 592.64°C (rough estimate)
• Appearance: /
• Density: 1.3824 (rough estimate)
• Refractive Index: 1.6910 (estimate)
• PKA: 12.66±0.70(Predicted)
• CAS DataBase Reference: streptothricin F(CAS DataBase Reference)
• NIST Chemistry Reference: streptothricin F(3808-42-2)
• EPA Substance Registry System: streptothricin F(3808-42-2)

Safety Data

• Hazardous Substances Data: 3808-42-2(Hazardous Substances Data)

Usage

Description

Streptothricin F is a member of the streptothricin family, which are a group of aminoglycoside-type antibiotics. It is characterized by a peptide side-chain consisting of a single unit of beta-lysine. This unique structure contributes to its potential antimicrobial properties and makes it a candidate for pharmaceutical applications.

Uses

Used in Pharmaceutical Industry:
Streptothricin F is used as an antibiotic agent for its antimicrobial properties. It is particularly effective against a range of bacteria, including both Gram-positive and Gram-negative strains. Its unique structure allows it to target specific bacterial components, inhibiting their growth and contributing to the treatment of various infections.
Additionally, due to its aminoglycoside nature, streptothricin F may be used in combination with other antibiotics to enhance their efficacy and combat antibiotic resistance. This application can be particularly valuable in the development of new antimicrobial therapies to address the growing global health concern of antibiotic resistance.

InChI:InChI=1/C19H34N8O8/c20-3-1-2-7(21)4-10(30)24-13-14(31)15(35-18(22)33)9(6-28)34-17(13)27-19-25-11-8(29)5-23-16(32)12(11)26-19/h7-9,11-15,17,28-29,31H,1-6,20-21H2,(H2,22,33)(H,23,32)(H,24,30)(H2,25,26,27)/t7?,8-,9-,11-,12+,13-,14+,15+,17-/m1/s1

Upstream product

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• 83663-07-4 {5-[(2S,3R,4S,5R,6R)-2-Allyloxy-4-benzyloxy-6-benzyloxymethyl-5-(2-methoxy-ethoxymethoxy)-tetrahydro-pyran-3-ylcarbamoyl]-4-benzyloxycarbonylamino-pentyl}-carbamic acid benzyl ester 
• 83670-98-8 [5-((2R,3R,4S,5R,6R)-4-Benzyloxy-6-benzyloxymethyl-5-carbamoyloxy-2-isothiocyanato-tetrahydro-pyran-3-ylcarbamoyl)-4-benzyloxycarbonylamino-pentyl]-carbamic acid benzyl ester 
• 83663-08-5 [5-((2S,3R,4S,5R,6R)-2-Allyloxy-4-benzyloxy-6-benzyloxymethyl-5-carbamoyloxy-tetrahydro-pyran-3-ylcarbamoyl)-4-benzyloxycarbonylamino-pentyl]-carbamic acid benzyl ester 
• 83663-06-3 {5-[(2S,4S,5R,6R)-2-Allyloxy-4-hydroxy-6-hydroxymethyl-5-(2-methoxy-ethoxymethoxy)-tetrahydro-pyran-3-ylcarbamoyl]-4-benzyloxycarbonylamino-pentyl}-carbamic acid benzyl ester 
• 83071-82-3 Acetic acid (3aR,4S,6R,7R,7aS)-4-allyloxy-7-(2-methoxy-ethoxymethoxy)-2-oxo-hexahydro-pyrano[3,4-d]oxazol-6-ylmethyl ester 
• 83663-04-1 allyl 6-O-acetyl-2-amino-2-N,3-O-carbonyl-2-deoxy-α-D-gulopyranoside 
• 83663-05-2 (3R,4S,5R,6R)-2-Allyloxy-3-amino-6-hydroxymethyl-5-(2-methoxy-ethoxymethoxy)-tetrahydro-pyran-4-ol 
• 83663-11-0 C₆₂H₇₆N₈O₁₅S 

Relevant articles and documents

TOTAL SYNTHESIS OF ANTIBIOTIC STREPTOTHRICIN F

The first total synthesis of streptothricin F was achieved and its structure was unequivocally confirmed.