380828-77-3

Basic information

• Product Name: 4-(4-CHLORO-PHENOXY)-CYCLOHEXYLAMINE HYDROCHLORIDE
• Synonyms: 4-(3-CHLORO-PHENOXY)-CYCLOHEXYLAMINE HYDROCHLORIDE;4-(4-CHLORO-PHENOXY)-CYCLOHEXYLAMINE HYDROCHLORIDE;4-(4-CHLORO-PHENOXY)-CYCLOHEXYLAMINE1HCLSALT;4-(4-CHLOROPHENOXY)CYCLOHEXANAMINE HCL
• CAS NO: 380828-77-3
• Molecular Formula: C12H17Cl2NO
• Molecular Weight: 262.17548
• Mol File: 380828-77-3.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-(4-CHLORO-PHENOXY)-CYCLOHEXYLAMINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-CHLORO-PHENOXY)-CYCLOHEXYLAMINE HYDROCHLORIDE(380828-77-3)
• EPA Substance Registry System: 4-(4-CHLORO-PHENOXY)-CYCLOHEXYLAMINE HYDROCHLORIDE(380828-77-3)

Safety Data

• Hazardous Substances Data: 380828-77-3(Hazardous Substances Data)

Upstream product

• 637-87-6 1-Chloro-4-iodobenzene 
• 27489-62-9 trans-4-aminocyclohexan-1-ol 
• 352-33-0 1-Chloro-4-fluorobenzene 
• 27489-62-9 trans-4-hydroxycyclohexylamine 

Relevant articles and documents

SUBSTITUTED UREA EIF2α KINASE ACTIVATORS

This disclosure relates to substituted urea eIF2α kinase activators including methods of making and using the same. For example, such activators can include cycloalkyl aryl ureas, which activate at least one eIF2α kinase. These compounds may be useful for treatment of diseases such as, for example, cancer, hemolytic anemia not caused by infectious agents, Wolcott-Rallison syndrome, neurodegenerative disease, tuberous sclerosis complex, fragile-X syndrome, autism spectrum disorder, and ribosomal defect disease.

N- versus O-arylation of aminoalcohols: Orthogonal selectivity in copper-based catalysts

Two complementary protocols for copper-catalyzed arylation of aminoalcohols were developed. Selective N-arylation was accomplished at room temperature using 2-isobutyrylcyclohexanone (a β-diketone) as supporting ligand, while selective O-arylation require