380899-52-5

Upstream product

• 13743-09-4 2-methyl-5-phenyl-1,3-thiazole-4-carboxylic acid 

Downstream Products

• 1097265-13-8 8-methyl-2-({(2S)-1-[(2-methyl-5-phenyl-1,3-thiazol-4-yl)carbonyl]-2-piperidinyl}methyl)imidazo[1,2-a]pyridine 
• 1097265-33-2 3-iodo-2-({(2S)-1-[(2-methyl-5-phenyl-1,3-thiazol-4-yl)carbonyl]-2-piperidinyl}methyl)imidazo[1,2-a]pyridine 
• 1097265-31-0 3-methyl-2-({(2S)-1-[(2-methyl-5-phenyl-1,3-thiazol-4-yl)carbonyl]-2-piperidinyl} methyl)imidazo[1,2-a]pyridine 
• 1097265-37-6 3-chloro-2-({(2S)-1-[(2-methyl-5-phenyl-1,3-thiazol-4-yl)carbonyl]-2-piperidinyl}methyl)-7-(trifluoromethyl)imidazo[1,2-a]pyridine 
• 1097265-39-8 3-fluoro-8-methyl-2-({(2S)-1-[(2-methyl-5-phenyl-1,3-thiazol-4-yl)carbonyl]-2-piperidinyl}methyl)imidazo[1,2-a]pyridine 
• 1097265-41-2 3-chloro-6-fluoro-2-({(2S)-1-[(2-methyl-5-phenyl-1,3-thiazol-4-yl)carbonyl]-2-piperidinyl}methyl)imidazo[1,2-a]pyridine 
• 1097265-43-4 8-(methyloxy)-2-({(2S)-1-[(2-methyl-5-phenyl-1,3-thiazol-4-yl)carbonyl]-2-piperidinyl} methyl)imidazo[1,2-a]pyridine 
• 1097265-45-6 3-chloro-7-(methyloxy)-2-({(2S)-1-[(2-methyl-5-phenyl-1,3-thiazol-4-yl)carbonyl]-2-piperidinyl} methyl)imidazo[1,2-a]pyridine 
• 1097265-47-8 6-fluoro-8-methyl-2-({(2S)-1-[(2-methyl-5-phenyl-1,3-thiazol-4-yl)carbonyl]-2-piperidinyl}methyl)imidazo[1,2-a]pyridine 
• 1097265-49-0 8-ethenyl-6-fluoro-2-({(2S)-1-[(2-methyl-5-phenyl-1,3-thiazol-4-yl)carbonyl]-2-piperidinyl}methyl)imidazo[1,2-a]pyridine 
• 1097265-30-9 5-fluoro-2-({(2S)-1-[(2-methyl-5-phenyl-1,3-thiazol-4-yl)carbonyl]-2-piperidinyl} methyl)imidazo[1,2-a]pyridine 
• 1097265-21-8 8-fluoro-2-({(2S)-1-[(2-methyl-5-phenyl-1,3-thiazol-4-yl)carbonyl]-2-piperidinyl}methyl)imidazo[1,2-a]pyridine 
• 1227853-94-2 6-chloro-7-methyl-2-({(2S)-1-[(2-methyl-5-phenyl-1,3-thiazol-4-yl)carbonyl]-2-piperidinyl}methyl)imidazo[1,2-b]pyridazine 
• 1227853-92-0 6-chloro-8-methyl-2-({(2S)-1-[(2-methyl-5-phenyl-1,3-thiazol-4-yl)carbonyl]-2-piperidinyl}methyl)imidazo[1,2-b]pyridazine 

Relevant academic research and scientific papers

PIPERIDINYL ALKYNE OREXIN RECEPTOR ANTAGONISTS

The present invention is directed to piperidinyl alkyne compounds which are antagonists of orexin receptors. The present invention is also directed to uses of the piperidinyl alkyne compounds described herein in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The present invention is also directed to pharmaceutical compositions comprising these compounds. The present invention is also directed to uses of these pharmaceutical compositions in the prevention or treatment of such diseases in which orexin receptors are involved.

NOVEL COMPOUNDS

This invention relates to imidazopyrimidine substituted piperidine derivatives and their use as pharmaceuticals.

NOVEL COMPOUNDS

This invention relates to imidazopyrazine substituted piperidine derivatives and their use as pharmaceuticals.

NOVEL COMPOUNDS

This invention relates to imidazopyridazine substituted piperidine derivatives and their use as pharmaceuticals.

NOVEL COMPOUNDS

Disclosed are imidazo[1,2-a]pyridin-2-ylmethyl substituted piperidine derivatives of formula (I) and their use as pharmaceuticals.

IMIDAZO [1, 2-C] PYRIMIDIN-2-YLMETHYLPIPERIDINES AS OREXIN RECEPTOR ANTAGONISTS

This invention relates to imidazo[1,2-c]pyrimidin-2-ylmethyl substituted piperidine derivatives and their use as pharmaceuticals.