38147-82-9 Usage
Amino Acid Derivative
Contains an amino acid structure
It is derived from an amino acid, which is a building block of proteins.
Cyclohexene Ring
Contains a six-membered carbon ring with alternating double bonds
The presence of the cyclohexene ring provides the compound with a specific structure and properties.
Acetic Acid Functional Group
Contains a carboxylic acid group (-COOH)
The acetic acid functional group contributes to the compound's reactivity and properties.
Chiral Molecule
(R)designation
The compound has a specific spatial arrangement of atoms, making it a chiral molecule with potential for different stereoisomers.
Potential Applications
Organic synthesis, pharmaceuticals, or as a building block for complex chemical structures
The compound may be used in various fields due to its unique structure and properties.
Stereochemistry
Specific spatial arrangement affects properties and potential uses
The compound's stereochemistry plays a crucial role in determining its reactivity, interactions, and applications.
Context-Dependent Properties
Properties and uses may vary depending on the specific stereochemistry and context of its application
The compound's properties and potential applications can change based on the specific conditions and requirements of its use.
Check Digit Verification of cas no
The CAS Registry Mumber 38147-82-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,8,1,4 and 7 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 38147-82:
(7*3)+(6*8)+(5*1)+(4*4)+(3*7)+(2*8)+(1*2)=129
129 % 10 = 9
So 38147-82-9 is a valid CAS Registry Number.
38147-82-9Relevant academic research and scientific papers
ASYMMETRIC SYNTHESES VIA HETEROCYCLIC INTERMEDIATES-XXII; ENANTIOSELECTIVE SYNTHESIS OF α-ALKENYL GLYCINE METHYL ESTERS AND α-ALKENYL GLYCINES (β,γ-UNSATURATED AMINO ACIDS)
Schoellkopf, Ulrich,Nozulak, Joachim,Groth, Ulrich
, p. 1409 - 1418 (2007/10/02)
Enantioselective syntheses of α-alkenyl glycines of type 10 and of type 23 are described that provide these uncommon amino acids with predictable configuration and with ee-values of >95percent.Both approaches are based on the bislactim ether method developed by Schoellkopf et al.As for 10: The lithiated bis-lactim ether 6 of cyclo(L-val-gly) is reacted with 2alkanals 2 to give the addition products 7 with de>95percent.These on acid hydrolysis afford L-valinate 8 and the methyl (2R)-2-amino-4-(dimethyl t-butyl)silyl-3-hydroxyalkanoates 9 which are convertible into the (R)-α-alkenyl glycines of type 10.The scope of this synthesis is limited by the fact that the compounds 9 are thermolabile when disubstituted at C-4.As for 23: The lithiated bis-lactim ether 6 is reacted with thioketones 14 to give the addition products 15 with de>95percent.The S-methyl compounds 16 undergo elimination to give regioselectively the olefins 18 when treated with Raney-Ni.Alternatively, the olefins 18 are obtained from the sulfonium salts 24 by dimethyl sulfide elimination, although this route is less regiospecific.The compounds 18 are cleaved by dilute hydrochloric acid, liberating L-valinate 8 and (R)-α-alkenyl glycine methyl esters 21, which on further hydrolysis yield (R)-α-alkenyl glycines 23.This synthesis is limited only by the availability of thioketones 14.
