38163-84-7

Basic information

• Product Name: N-(2-Methylamino-phenyl)-toluol-sulfonsaeure-⁽⁴⁾-amid
• Synonyms: N-(2-Methylamino-phenyl)-toluol-sulfonsaeure-⁽⁴⁾-amid
• CAS NO: 38163-84-7
• Molecular Weight: 276.359
• Mol File: 38163-84-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(2-Methylamino-phenyl)-toluol-sulfonsaeure-⁽⁴⁾-amid(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-Methylamino-phenyl)-toluol-sulfonsaeure-⁽⁴⁾-amid(38163-84-7)
• EPA Substance Registry System: N-(2-Methylamino-phenyl)-toluol-sulfonsaeure-⁽⁴⁾-amid(38163-84-7)

Safety Data

• Hazardous Substances Data: 38163-84-7(Hazardous Substances Data)

Upstream product

• 25446-46-2 toluene-4-sulfonic acid-(2-amino-N-methyl-anilide) 
• 205642-00-8 1-(N-methyl-N-4-toluenesulfonylamino)-2-(N-4-toluenesulfonylamino)benzene 

Relevant articles and documents

Cleavage of sulfonamides with phenyldimethylsilyllithium

The toluene-p-sulfonamides of secondary amines and indoles are cleaved by treatment with phenyldimethylsilyllithium to give the secondary amines. Aziridine toluene-p-sulfonamides, however, are opened by attack of the silyllithium reagent on carbon to give β-silylethyl sulfonamides. The aziridine toluene-p-sulfonamide 22 derived from norbornene is different in giving the 2-[dimethyl(phenyl)silyl]-4-methylbenzenesulfonamide 23 of exo-norbornylamine. The aziridine toluene-p-sulfonamides 26, 28 and 30, derived from methyl cinnamate, methyl acrylate and cinnamyl acetate, are also anomalous, giving 3-[N-(p-tolylsulfonyl)amino]-3-phenylpropionic acid 27, {3-[N-(p-tolylsulfonyl)amino]propionyl}-dimethyl(phenyl)silane 29 and trans-cinnamyl alcohol 31, respectively, each derived by opening of the aziridine ring followed by loss of the silyl group.