381670-30-0

Basic information

• Product Name: (3R)-(+)-3-(ETHYLAMINO)PYRROLIDINE
• Synonyms: (3R)-(+)-3-(ETHYLAMINO)PYRROLIDINE;3-Pyrrolidinamine,N-ethyl-,(3R)-(9CI);(3R)-(+)-3-(ETHYLAMINO)PYRROLIDINE 96+%;(R)-N-ethylpyrrolidin-3-amine;(3R)-N-Ethyl-3-pyrrolidinamine;(3R)-(+)-3-(Ethylamino)pyrrolidine
• CAS NO: 381670-30-0
• Molecular Formula: C6H14N2
• Molecular Weight: 114.19
• Product Categories: AMINESECONDARY;3-Aminopyrrolidines;Amines (Chiral);Chiral 3-Aminopyrrolidines;Chiral Building Blocks;Synthetic Organic Chemistry
• Mol File: 381670-30-0.mol

Chemical Properties

• Boiling Point: 176 °C
• Flash Point: 54℃
• Appearance: /
• Density: 0,92 g/cm3
• Vapor Pressure: 1.68mmHg at 25°C
• Refractive Index: 14.5 ° (C=10, EtOH)
• Storage Temp.: 2-8°C
• PKA: 10.59±0.10(Predicted)
• CAS DataBase Reference: (3R)-(+)-3-(ETHYLAMINO)PYRROLIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: (3R)-(+)-3-(ETHYLAMINO)PYRROLIDINE(381670-30-0)
• EPA Substance Registry System: (3R)-(+)-3-(ETHYLAMINO)PYRROLIDINE(381670-30-0)

Safety Data

• Statements: 10-34
• Safety Statements: 26-36/37/39
• RIDADR: 2734
• HazardClass: 8/3
• PackingGroup: II
• Hazardous Substances Data: 381670-30-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical and Agrochemical Synthesis:
(3R)-(+)-3-(ETHYLAMINO)PYRROLIDINE is used as a chiral auxiliary for the asymmetric synthesis of compounds, contributing to the production of pharmaceuticals and agrochemicals. Its presence helps control the stereochemistry of the products, ensuring the desired chiral purity and enhancing the effectiveness of the synthesized compounds.
Used in Asymmetric Synthesis Reactions:
In the field of organic chemistry, (3R)-(+)-3-(ETHYLAMINO)PYRROLIDINE is utilized as a resolving agent, catalyst, or ligand in asymmetric synthesis reactions. Its role in these reactions is crucial for controlling the stereochemistry, which is essential for the biological activity and selectivity of the final products.
Used in the Development of New Drugs and Materials:
Owing to its unique chiral properties, (3R)-(+)-3-(ETHYLAMINO)PYRROLIDINE has potential applications in the research and development of new drugs and materials. Its versatility allows for its use in various innovative applications, contributing to advancements in medicinal chemistry and material science.

InChI:InChI=1/C6H14N2/c1-2-8-6-3-4-7-5-6/h6-8H,2-5H2,1H3/t6-/m1/s1

Upstream product

• 115445-21-1 (R)-1-benzyl-N-ethylpyrrolidine-3-amine 

Relevant articles and documents

BIS-PYRIDYLPYRIDONES AS MELANIN-CONCENTRATING HORMONE RECEPTOR 1 ANTAGONISTS

The invention provides novel bis-pyridylpyridones which are antagonists at the melanin-concentrating hormone receptor 1 (MCHR1), pharmaceutical compositions containing them, processes for their preparation, and their use in therapy and for the treatment of obesity and/or diabetes.