381677-75-4 Usage
General Description
4-(3-fluorophenyl)dihydro-2H-pyran-2,6(3H)-dione, also known as rosmarinic acid, is a compound found in various plants, particularly in the Lamiaceae family. It has been studied for its potential antioxidant, anti-inflammatory, and anti-cancer properties. Rosmarinic acid has shown promise in protecting cells from oxidative stress and inflammation, as well as inhibiting the growth of cancer cells. It has also been investigated for its potential benefits in treating various health conditions, including allergies, asthma, and cardiovascular diseases. Overall, 4-(3-fluorophenyl)dihydro-2H-pyran-2,6(3H)-dione has gained attention for its potential therapeutic and health-promoting effects, making it a substance of interest in research and drug development.
Check Digit Verification of cas no
The CAS Registry Mumber 381677-75-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,8,1,6,7 and 7 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 381677-75:
(8*3)+(7*8)+(6*1)+(5*6)+(4*7)+(3*7)+(2*7)+(1*5)=184
184 % 10 = 4
So 381677-75-4 is a valid CAS Registry Number.
381677-75-4Relevant articles and documents
Synthesis of 2,5-thiazole butanoic acids as potent and selective αvβ3 integrin receptor antagonists with improved oral pharmacokinetic properties
Wendt, John A.,Wu, Hongwei,Stenmark, Heather G.,Boys, Mark L.,Downs, Victoria L.,Penning, Thomas D.,Chen, Barbara B.,Wang, Yaping,Duffin, Tiffany,Finn, Mary Beth,Keene, Jeffery L.,Engleman, V. Wayne,Freeman, Sandra K.,Hanneke, Melanie L.,Shannon, Kristen E.,Nickols, Maureen A.,Steininger, Christina N.,Westlin, Marissa,Klover, Jon A.,Westlin, William,Nickols, G. Allen,Russell, Mark A.
, p. 845 - 849 (2007/10/03)
We describe a series of 2,5 thiazole containing compounds, which are potent antagonists of the integrin αvβ3 and show selectivity relative to the other integrins, such as αIIbβ 3 and αvβ6. These analogs were demonstrated to have high bioavailability relative to other relative heterocyclic analogs.