38171-50-5Relevant academic research and scientific papers
Ene-carbonyl reductive coupling mediated by zinc and ammonia for the synthesis of γ-hydroxybutyric acid derivatives
Yeh, Chien-Hung,Korivi, Rajendra Prasad,Cheng, Chien-Hong
supporting information, p. 1338 - 1344 (2013/06/27)
The reductive coupling of an aryl carbonyl group with an activated alkene to give the corresponding γ-hydroxybutyric acid (GHBA) derivative was achieved in the presence of zinc and ammonia. A board scope of GHBA derivatives could be synthesized under ambient conditions by this method. A mechanism involving a Zn-ketyl radical as the key intermediate is proposed. Copyright
7,7A-Dihydro-4-[2-(3-alkoxyphenyl)-2-hydroxyethyl]-7a-alkyl-1, 5(6H)-indandiones,3,4,8,8a-tetrahydro-5-[2-(3-alkoxyphenyl)-2-hydroxyethyl]-8a-alkyl-1,6(7H)-naphthalenediones and processes for the preparation thereof utilizing asymmetric induction
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, (2008/06/13)
A multi-step, stereospecific total synthesis of steroids is disclosed. The starting materials for this process are the relatively inexpensive and readily available m-alkoxy acetophenones. The process is suitable for the preparation of racemic or optically
