38175-99-4

Basic information

• Product Name: (R)-(+)-Verapamilic Acid
• Synonyms: (R)-(+)-Verapamilic Acid;(R)-4-Cyano-4-(3,4-dimethoxyphenyl)-5-methylhexanoic Acid;(R)--Cyano-3,4-dimethoxy--(1-methylethyl)-benzenebutanoic Acid
• CAS NO: 38175-99-4
• Molecular Formula: C16H21NO4
• Molecular Weight: 0
• Product Categories: Aromatics Compounds;Aromatics;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 38175-99-4.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 448.795°C at 760 mmHg
• Flash Point: 225.224°C
• Appearance: /
• Density: 1.127g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.515
• Storage Temp.: Hygroscopic, Refrigerator, under inert atmosphere
• Solubility: Chloroform, Dichloromethane (Slightly), Ethanol (Slightly), Methanol (Slightly)
• Stability: Hygroscopic
• CAS DataBase Reference: (R)-(+)-Verapamilic Acid(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-(+)-Verapamilic Acid(38175-99-4)
• EPA Substance Registry System: (R)-(+)-Verapamilic Acid(38175-99-4)

Safety Data

• Hazardous Substances Data: 38175-99-4(Hazardous Substances Data)

Usage

Chemical Properties

White Solid

Uses

Different sources of media describe the Uses of 38175-99-4 differently. You can refer to the following data:
1. Precursor for Verapamil. Calcium antagonist
2. Precursor for Verapamil. Calcium antagonist.

InChI:InChI=1/C16H21NO4/c1-11(2)16(10-17,8-7-15(18)19)12-5-6-13(20-3)14(9-12)21-4/h5-6,9,11H,7-8H2,1-4H3,(H,18,19)/t16-/m1/s1

Upstream product

• 36770-70-4 2-(3,4-dimethoxyphenyl)-5-hydroxy-2-(methylethyl)pentanenitrile 
• 20850-49-1 2-(3,4-dimethoxyphenyl)-3-methylbutyronitrile 
• 3886-69-9 (R)-1-phenyl-ethyl-amine 
• 36622-23-8 4-cyano-4-(3,4-dimethoxyphenyl)-5-methyl hexanoic acid 
• 2627-86-3 (S)-1-phenyl-ethylamine 
• 102201-30-9 4-(3 4-dimethoxyphenyl)-4-cyano-5-methylcapronitrile 

Downstream Products

• 204642-98-8 (S)-verapamilamide 
• 204642-98-8 (R)-verapamilamide 
• 36622-28-3 (-)-Verapamil hydrochloride 
• 152-11-4 (+)-Verapamil hydrochloride 
• 36622-24-9 (S)-verapamilic acid 
• 36622-24-9 (R)-verapamilic acid 
• 204642-98-8 verapamilamide 

Relevant articles and documents

Design, synthesis, and preliminary pharmacological evaluation of 4-aminopiperidine derivatives as N-type calcium channel blockers active on pain and neuropathic pain

Several compounds with a 4-aminopiperidine scaffold decorated on both nitrogen atoms by alkyl or acyl moieties containing the structural motifs of verapamil and of flunarizine, as well as those that are more frequent in known N-type calcium channel antago