3818-94-8Relevant academic research and scientific papers
Use of weak opioids and mixed opioid agonists/antagonists for treatment of urinary incontinence
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, (2008/06/13)
A pharmaceutical composition for the treatment of an increased urge to urinate or urinary incontinence, comprising an effective amount of at least a compound selected from the group consisting of codeine, dihydrocodeine, dextropropoxyphene, meptazinol and tilidine. Also disclosed are methods of treatment using the pharmaceutical compositions and preferred dosages for the treatment methods.
Synthesis and purification of d-propoxyphene hydrochloride
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, (2008/06/13)
New and improved synthesis of α-d-propoxyphene hydrochloride by acid chloride reaction between propionyl chloride and α-d-1,2-diphenyl-3-methyl-4-dimethylamino-2-butanol (d-oxyphene) with small amounts of thionyl chloride improves yield and substantially simplifies purification.
Polypeptide propoxyphene derivatives for immunoassay reagents
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, (2008/06/13)
Novel compounds are provided which are derivatives of 1,2-diphenyl-3-methyl-4-dimethylamino-2-butanol. The indicated alcohol is employed to prepare the monoester of a dibasic acid which is conjugated with an antigen for the production of antibodies which recognize both propoxyphene and its N-desmethyl metabolite in immunoassays.
