38183-12-9 Usage
Chemical Properties
white powder
Uses
Different sources of media describe the Uses of 38183-12-9 differently. You can refer to the following data:
1. Fluorescamine is a non-fluorescent reagent that reacts readily under mild conditions with primary amines in amino acids and peptides to form stable, highly fluorescent compounds. Reaction takes place under mild conditions. Low background due to hydrolysis.
2. For fluorescent detection of amino acids, peptides and proteins.Fluorescamine plays an important role as a reagent for the detection of amines, peptides and proteins. It is also used as a substrate for measuring protease activity. It is utilized in the detection and quantitation of residual aminopenicillins and sulfonamides in honey by HPLC. It finds application in the determination of lisinopril in human plasma and urine.
Synthesis Reference(s)
Journal of the American Chemical Society, 94, p. 5927, 1972 DOI: 10.1021/ja00771a084
Purification Methods
Fluram is a non-fluorescent reagent that reacts with primary amines to form highly fluorescent compounds. Purify it by dissolving (~1g) in Et2O/*C6H6 (1:1, 180 mL), washing with 1% aqueous NaHCO3 (50mL), drying (Na2SO4), and evaporating in a vacuum. Dissolve the residue in warm CH2Cl2 (5mL), dilute with Et2O (12mL) and refrigerate. Collect the solid and dry it in a vacuum. IR (CHCl3): 1810, 1745, 1722, 1625 and 1600 cm-1, and 1HNMR (CDCl3): 8.71 (s, -OHC=). [Weigele et max al. J Am Chem Soc 94 5927 1972, Weigele et al. J Org Chem 41 388 1976, Lai Methods Enzymol 47 236 1977.] Forskolin (Colforsin, Coleonol, 5-[acetyloxy]-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7, 10a-penta-methyl-[3R -{3
Check Digit Verification of cas no
The CAS Registry Mumber 38183-12-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,8,1,8 and 3 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 38183-12:
(7*3)+(6*8)+(5*1)+(4*8)+(3*3)+(2*1)+(1*2)=119
119 % 10 = 9
So 38183-12-9 is a valid CAS Registry Number.
InChI:InChI=1/C17H10O4/c18-15-13(11-6-2-1-3-7-11)10-20-17(15)14-9-5-4-8-12(14)16(19)21-17/h1-10H/t17-/m1/s1
38183-12-9Relevant articles and documents
Technological method for preparing fluorescent amine (by machine translation)
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Paragraph 0043; 0049-0057; 0059; 0065-0073, (2020/05/30)
The method, comprises the following steps: steps: reaction of an indene triketone compound as a raw material, with a phenylacetaldehyde compound in a proper amount of catalyst to obtain the diepoxide, and; reaction of the starting: with a proper amount of an oxidizing agent to obtain the diepoxide compound, has a short synthesis route, process and a simple, reaction. yield. (by machine translation)
Enkephalin analogues
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, (2008/06/13)
Compounds corresponding in structure to enkephalin or polypeptide analogues thereof, wherein one or more peptide links of the enkephalin or analogue is represented by a group or groups the same or different selected from dimethylene, methylene-imino and keto-methylene groups.