3819-20-3Relevant academic research and scientific papers
Direct Conversion of 13β-Alkylgonatetraenes into 13β-Alkylgon-4-en-3-ones
Bijoy, Panicker,Ramachandran, Uma,Rao, G. S. R. Subba
, p. 2331 - 2334 (1994)
Birch reduction of 8,9-didehydroestradiol-17β 3-methyl ether 1 or 9(11)-didehydroestradiol-17β 3 methyl ether 2 followed by acid hydrolysis results in a mixture of 19-nortestosterone 8 and 19-nor-9β,10α-testosterone 9 in varying amounts.However, reduction of their acetates with sodium or lithium, tert-butyl alcohol in liquid ammonia and in the presence of aniline affords exclusively 19-nortestosterone.Similarly, 18α-homo-19-nortestosterone 12 is prepared from the acetate of 18α-homoestradiol-17β 3 methyl ether, 10.
