Yellow Crystalline Solid
A non-steroidal anti-inflammatory agent. An anti-inflammatory
Sulindac is a non-steroidal anti-inflammatory drug.
Used in Particular Diseases
Acute Gouty Arthritis:
Dosage and Frequency: 200 mg twice daily for 7–10 days
Prodrug. Metabolizes to sulindac sulfide, a cyclooxgenase inhibitor that represses ras signaling, and sulindac sulfone, an antitumor agent, following oral administration in vivo . Widely used anti-inflammatory agent.
ChEBI: A monocarboxylic acid that is 1-benzylidene-1H-indene which is substituted at positions 2, 3, and 5 by methyl, carboxymethyl, and fluorine respectively, and in which the phenyl group of the benzylidene moiety is substituted at the
ara position by a methylsulfinyl group. It is a prodrug for the corresponding sulfide, a non-steroidal anti-inflammatory drug, used particularly in the treatment of acute and chronic inflammatory conditions.