382-12-7

Basic information

• Product Name: 3,3-Dibromo-2-oxo-1,1,1-trifluorobutane
• Synonyms: 3,3-Dibromo-1,1,1-trifluorobutan-2-one;3,3-Dibromo-2-oxo-1,1,1-trifluorobutane
• CAS NO: 382-12-7
• Molecular Formula: C₄H₃Br₂F₃O
• Molecular Weight: 283.8692296
• Mol File: 382-12-7.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 124 °C
• Appearance: /
• Density: 2 +-.0.06 g/cm3(Predicted)
• CAS DataBase Reference: 3,3-Dibromo-2-oxo-1,1,1-trifluorobutane(CAS DataBase Reference)
• NIST Chemistry Reference: 3,3-Dibromo-2-oxo-1,1,1-trifluorobutane(382-12-7)
• EPA Substance Registry System: 3,3-Dibromo-2-oxo-1,1,1-trifluorobutane(382-12-7)

Safety Data

• Hazardous Substances Data: 382-12-7(Hazardous Substances Data)

Usage

General Description

3,3-Dibromo-2-oxo-1,1,1-trifluorobutane is a chemical compound with the molecular formula C4H3Br2F3O. It is a highly reactive and potentially hazardous compound that is used in organic synthesis and pharmaceutical research. Its main applications include as a building block for the synthesis of various organic compounds and as a reagent in chemical reactions. It is known for its strong odor and flammable properties, and is commonly handled with caution in laboratory settings. Due to its chemical structure and properties, 3,3-Dibromo-2-oxo-1,1,1-trifluorobutane is considered a potentially toxic and environmentally hazardous substance, and should be handled and disposed of according to proper safety and regulatory guidelines.

Upstream product

• 381-88-4 1,1,1-trifluoro-2-butanone 
• 382-01-4 3-bromo-1,1,1-trifluoro-2-butanone 

Downstream Products

• 188490-63-3 3,3,3-trifluoro-2-oxopropanal 1-(4-chloro-2-fluoro-5-hydroxyphenylhydrazone) 
• 131549-62-7 1,1,1-trifluoro-2,3-butanedione 
• 143309-87-9 6,7-dichloro-2-(trifluoromethyl)-3-methylquinoxaline 

Relevant articles and documents

PYRAZOLE DERIVATIVES HAVING KINASE MODULATING ACTIVITY

The invention provides a compound of the formula (I): or a salt, tautomer, N-oxide or solvate thereof; wherein A is selected from a bond, CH2 and CH(CN); Rl is selected from: (i) a cycloalkyl group of 3 to 6 ring members optionally substituted by one or more substituents selected from methyl, ethyl, hydroxy, methoxy, ethoxy, fluorine, amino and cyano; (ii) a phenyl group optionally substituted by up to three substituents selected from methyl, ethyl, fluorine, chlorine, methoxy, ethoxy and methylsulphonyl, but excluding 2,6-difluorophenyl, 2-fluoro-6-methoxy and 5-chloro-2-methoxyphenyl; (iii) a monocyclic heterocyclic group selected from furyl and isoxazolyl, the heterocyclic group being optionally substituted by one or two groups selected from methyl, ethyl, and a group CH2R2 where R2 is a five or six membered saturated heterocyclic ring containing one or two heteroatom ring members selected from O and N, the heterocyclic ring being optionally substituted by one or two methyl groups; and (iv) a bicyclic heterocyclic group selected from 2,3-dihydrobenzofuranyl and benzo[c]isoxazolyl, the bicyclic group being optionally substituted by one or two substituents selected from methyl, ethyl, hydroxy, methoxy, ethoxy, fluorine, amino, cyano and chlorine, the bicyclic heterocyclic group being other than a 2,2-dimethyl-2,3-dihydrobenzofuran-7-yl group.

Pyridazin-3-one derivatives, their use, and intermediates for their production

PCT No. PCT/JP96/02311 Sec. 371 Date Jan. 30, 1998 Sec. 102(e) Date Jan. 30, 1998 PCT Filed Aug. 19, 1996 PCT Pub. No. WO97/07104 PCT Pub. Date Feb. 27, 1997Novel pyridazin-3-one derivatives of formula [1] are provided, which are useful as active ingredie