382-76-3

Basic information

• Product Name: 2-chloro-4-nitro-1-(trifluoromethylsulfonyl)benzene
• Synonyms: 2-chloro-4-nitro-1-(trifluoromethylsulfonyl)benzene
• CAS NO: 382-76-3
• Molecular Weight: 289.619
• Mol File: 382-76-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-chloro-4-nitro-1-(trifluoromethylsulfonyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-4-nitro-1-(trifluoromethylsulfonyl)benzene(382-76-3)
• EPA Substance Registry System: 2-chloro-4-nitro-1-(trifluoromethylsulfonyl)benzene(382-76-3)

Safety Data

• Hazardous Substances Data: 382-76-3(Hazardous Substances Data)

Upstream product

• 2926-29-6 Langlois reagent 
• 121-87-9 2-Chloro-4-nitroaniline 
• 387-93-9 (2-chloro-4-nitro-phenyl)-trifluoromethyl sulfoxide 
• 450-97-5 (2-chloro-4-nitro-phenyl)-trifluoromethyl sulfide 

Downstream Products

• 29688-13-9 2-Chloro-4-methoxyphenyl-trifluormethyl-sulfon 
• 350-30-1 3-chloro-4-fluoronitrobenzene 

Relevant articles and documents

Copper-Promoted Trifluoromethanesulfonylation and Trifluoromethylation of Arenediazonium Tetrafluoroborates with NaSO2CF3

A tunable chemoselective trifluoromethanesulfonylation and trifluoromethylation of arenediazonium tetrafluoroborates with Langlois' reagent (NaSO2CF3) was developed. The Cu2O-catalyzed reaction in DMSO gave aryl trifluoromethanesulfones as the major products. On the other hand, the trifluoromethylated arenes were produced in the presence of oxidant tert-butyl hydroperoxide, CuBF4(MeCN)4, and 2,2′;6′,2 terpyridine (tpy). Both of these transformations proceed under mild conditions and tolerate functional groups.