38220-78-9 Usage
Uses
Used in Pharmaceutical Industry:
5-Bromo-2-chloromethylbenzofuran is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of new drugs with improved therapeutic properties. Its unique structure and halogenated nature facilitate the creation of novel molecular entities with potential applications in treating a range of diseases.
Used in Agrochemical Industry:
In the agrochemical sector, 5-Bromo-2-chloromethylbenzofuran is utilized as a building block in the synthesis of agrochemicals, such as pesticides and herbicides. Its incorporation into these compounds can enhance their effectiveness in controlling pests and weeds, thereby contributing to increased crop yields and agricultural productivity.
Used in Medicinal Chemistry Research:
5-Bromo-2-chloromethylbenzofuran serves as a valuable research tool in medicinal chemistry, where it is employed to explore its biological activity and structural features. This research can lead to a better understanding of its potential applications in drug discovery and the development of new therapeutic agents.
Used in Chemical Synthesis:
As a halogenated benzofuran derivative, 5-Bromo-2-chloromethylbenzofuran is used in various chemical synthesis processes. Its reactivity and functional groups make it a versatile building block for creating a wide range of organic compounds with diverse applications in different industries.
Check Digit Verification of cas no
The CAS Registry Mumber 38220-78-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,8,2,2 and 0 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 38220-78:
(7*3)+(6*8)+(5*2)+(4*2)+(3*0)+(2*7)+(1*8)=109
109 % 10 = 9
So 38220-78-9 is a valid CAS Registry Number.
InChI:InChI=1/C9H6BrClO/c10-7-1-2-9-6(3-7)4-8(5-11)12-9/h1-4H,5H2
38220-78-9Relevant academic research and scientific papers
Chromium-Catalyzed Asymmetric Dearomatization Addition Reactions of Halomethyl Heteroarenes
Tian, Qingshan,Bai, Jing,Chen, Bin,Zhang, Guozhu
supporting information, p. 1828 - 1831 (2016/05/19)
The first asymmetric dearomatization addition reaction of halomethyl arenes including benzofuran and benzothiophene was enabled by chromium catalysis. A variety of aldehydes served as suitable electrophiles under mild reaction conditions. Molecular complexities are quickly increased in a highly diastereo- and enantioselective manner.
SUBSTITUTED 2-AZA-BICYCLO[2.2.1]HEPTANE-3-CARBOXYLIC ACID (CYANO-METHYL)-AMIDES INHIBITORS OF CATHEPSIN C
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Page/Page column 70; 71; 72, (2014/09/29)
This invention relates to 2-Aza-bicyclo[2.2.1]heptane-3-carboxylic acid (cyano-methyl)-amides of formula (1) and their use as inhibitors of Cathepsin C, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of diseases connected with dipeptidyl peptidase I activity, e.g. respiratory diseases.
