38232-80-3Relevant academic research and scientific papers
Stereoselective addition of aliphatic thiols to internal alkynes in a catalytic system with palladium nanosalt as an active site
Orlov,Chistyakov,Starikova,Ananikov,Beletskaya
, p. 47 - 54 (2013/11/19)
An efficient catalytic system based on easily available palladium acetate was developed for the selective addition of aliphatic thiols to the triple bond of internal alkynes. Formed in situ [M(SR)2] n nanostructured particles were found to be an active form of the catalyst. It was experimentally confirmed for the first time that the most active form of the catalyst for thiol addition to internal alkynes is formed only in the reaction mixture containing the both reactants, namely, alkyne and thiol.
Asymmetric hydrogenation of alkyl(vinyl)thioethers: a promising approach to α-chiral thioethers
Meindertsma, Alex F.,Pollard, Michael M.,Feringa, Ben L.,de Vries, Johannes G.,Minnaard, Adriaan J.
, p. 2849 - 2858 (2008/09/17)
This paper describes the enantioselective hydrogenation of vinylthioethers. We show that thioether derivatives of maleic esters can be hydrogenated with full conversion and up to 60% ee, and that α-thioether cinnamic acids can be hydrogenated in 51% ee with modest conversion.
