382606-10-2Relevant academic research and scientific papers
Synthesis and antibacterial activity of a novel series of acylides: 3-O-(3-pyridyl)acetylerythromycin A derivatives
Tanikawa, Tetsuya,Asaka, Toshifumi,Kashimura, Masato,Suzuki, Keiko,Sugiyama, Hiroyuki,Sato, Masakazu,Kameo, Kazuya,Morimoto, Shigeo,Nishida, Atsushi
, p. 2706 - 2715 (2003)
A novel series of acylides, 3-O-(aryl)acetylerythromycin A derivatives, were synthesized and evaluated. These compounds have significant potent antibacterial activity against not only Gram-positive pathogens, including inducibly macrolide-lincosamide-stre
Synthesis and antibacterial activity of acylides (3-O-acyl-erythromycin derivatives): A novel class of macrolide antibiotics
Tanikawa,Asaka,Kashimura,Misawa,Suzuki,Sato,Kameot,Morimoto,Nishida
, p. 4027 - 4030 (2007/10/03)
Introduction of an acyl group to the 3-O-position of erythromycin A derivatives instead of L-cladinose led to a novel class of macrolide antibiotics that we named "acylides". The 3-O-nitrophenylacetyl derivative TEA0777 showed significantly potent activit
