38273-18-6

Upstream product

• 86639-19-2 5-benzyloxy-2-bromo-4-methoxyphenylacetic acid chloride 
• 342901-84-2 N-[2-(5-benzyloxy-2-bromo-4-methoxyphenyl)ethyl]-N-[(S)-1-phenylethyl]-2-(2-bromo-4,5-dimethoxyphenyl)acetamide 
• 342901-86-4 N-[2-(2-bromo-5-hydroxy-4-methoxyphenyl)ethyl]-N-[(S)-1-phenylethyl]-2-(2-bromo-4,5-dimethoxyphenyl)acetamide 
• 342901-80-8 N-[(S)-1-phenylethyl]-2-(5-benzyloxy-2-bromo-4-methoxyphenyl)acetamide 
• 342901-82-0 N-[(S)-1-phenylethyl]-2-(5-benzyloxy-2-bromo-4-methoxyphenyl)ethylamine 
• 13425-04-2 5-benzyloxy-4-methoxy-2-bromophenylacetic acid 

Relevant academic research and scientific papers

Bischler-napieralski cyclization of N-[2-(2-bromo-5-hydroxy-4-methoxyphenyl)ethyl]-n-[(S) -1-phenylethyl]-2-(2-bromo-4,5-dimethoxyphenyl)acetamide accompanied by elimination of chiral auxiliary

N-[2-(2-Bromo-5-hydroxy-4-methoxyphenyl)ethyl] -N-[(S)-1-phenylethyl]-2-(2-bromo-4,5-dimethoxyphenyl)acetamide (5) was cyclized under N-dealkylation at the 2-position to the racemic 1-benzyl-1,2,3,4 -tetrahydroisoquinoline derivatives (6) by the Bischler-