383159-30-6Relevant academic research and scientific papers
Synthesis method of benzofuran compound
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Paragraph 0053-0060; 0062; 0063, (2021/05/19)
The invention belongs to the field of organic chemical synthesis, and particularly relates to a synthesis method of a benzofuran compound. According to the invention, the reaction system adopts economical and efficient iron phthalocyanine as a catalyst, a
Palladium-catalyzed paraformaldehyde insertion: A three-component synthesis of benzofurans
Cheng, Xiufang,Peng, Yi,Wu, Jun,Deng, Guo-Jun
supporting information, p. 2819 - 2823 (2016/03/12)
An efficient procedure for 2-aroylbenzofuran preparation from 2-bromophenols, phenacyl bromides and paraformaldehyde is described. The cheap and stable paraformaldehyde served as the carbon source via an in situ formylation reaction.
Benzofuran derivatives as a novel class of inhibitors of mTOR signaling
Salomé, Christophe,Narbonne, Vanessa,Ribeiro, Nigel,Thuaud, Frédéric,Serova, Maria,De Gramont, Armand,Faivre, Sandrine,Raymond, Eric,Désaubry, Laurent
, p. 41 - 49 (2014/02/14)
High-throughput screening (HTS) hit 1 was previously identified as an inhibitor of the Akt/mTOR (Akt/mammalian target of rapamycin) signaling, which is a major target in oncology. The cytotoxicity of 1 was determined on a panel of human cancer cells lines
Heterocyclic compounds useful as malonyl-CoA decarboxylase inhibitors
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Page/Page column 15, (2010/02/10)
The present invention provides methods for the use of compounds as depicted by structure I, pharmaceutical compositions containing the same, and methods for the prophylaxis, management and treatment of metabolic diseases and diseases modulated by MCD inhi
