383175-93-7

Upstream product

• 17878-23-8 3,5-dibromo-1-trimethylsilylbenzene 
• 73183-34-3 bis(pinacol)diborane 
• 768-32-1 trimethylphenylsilane 
• 25015-63-8 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane 
• 626-39-1 1,3,5-trisbromobenzene 

Downstream Products

• 666257-70-1 3,5-bis{3,5-dimethyl-4-(diazo[9-{10-(4-tert-butyl-2,6-dimethylphenyl)anthryl}]methyl)phenyl}benzene 
• 383175-98-2 C₆₉H₈₆O₁₆Si 

Relevant academic research and scientific papers

Synthesis of a Contrapositionally Substituted Cyclohexa- meta -phenylene: A Ready-to-Use Precursor for Cyclohexa- meta -phenylene-Based Materials

A contrapositionally substituted derivative of cyclohexa- meta -phenylene ([6]CMP) was synthesized by an intramolecular Yamamoto coupling reaction of an appropriate terphenyl unit containing a trimethylsilyl substituent. Iododesilylation of the trimethyls

Molecular assembly of a pyridine functionalized janusarene

We describe a janusarene derivative PyJ, which forms micrometer-scale one-dimensional metallo-supramolecular polymer through coordination driven self-assembly. PyJ is a well-preorganized dodecatopic pyridyl ligand built on a hexaphenylbenzene platform. The two-face structural feature of PyJ allows for a delicate control over multiple Py-Ag+-Py coordination interactions, leading to assembled structure of PyJ-Ag+, which was characterized by dynamic light scattering, atomic force microscopy, and transmission electron microscopy.

Remote steric control for undirected meta-selective C-H activation of arenes

Regioselective functionalization of arenes remains a challenging problem in organic synthesis. Steric interactions are often used to block sites adjacent to a given substituent, but they do not distinguish the remaining remote sites. We report a strategy

Para -C-H borylation of benzene derivatives by a bulky iridium catalyst

A highly para-selective aromatic C-H borylation has been accomplished. By a new iridium catalyst bearing a bulky diphosphine ligand, Xyl-MeO-BIPHEP, the C-H borylation of monosubstituted benzenes can be affected with para-selectivity up to 91%. This catalytic system is quite different from the usual iridium catalysts that cannot distinguish meta- and para-C-H bonds of monosubstituted benzene derivatives, resulting in the preferred formation of meta-products. The para-selectivity increases with increasing bulkiness of the substituent on the arene, indicating that the regioselectivity of the present reaction is primarily controlled by steric repulsion between substrate and catalyst. Caramiphen, an anticholinergic drug used in the treatment of Parkinsons disease, was converted into five derivatives via our para-selective borylation. The present [Ir(cod)OH]2/Xyl-MeO-BIPHEP catalyst represents a unique, sterically controlled, para-selective, aromatic C-H borylation system that should find use in streamlined, predictable chemical synthesis and in the rapid discovery and optimization of pharmaceuticals and materials.

Preparation of Oligodiazo Compounds by Using the Suzuki Coupling Reaction and Characterization of Their Photoproducts

[9-{10-(4-tert-Butyl-2,6-dimethyl)phenyl}anthryl](4-bromo-2, 6-dimethylphenyl)diazomethane was found to be stable enough to survive under Suzuki coupling conditions and underwent mono-, di-, and trisubstitution with benzene mono-, di-, and triboronic acid