383184-30-3Relevant academic research and scientific papers
Synthesis, biological evaluation, and molecular modeling studies of a novel, peripherally selective inhibitor of catechol-O-methyltransferase
Learmonth, David A.,Palma, P. Nuno,Vieira-Coelho, Maria A.,Soares-Da-Silva, Patrício
, p. 6207 - 6217 (2007/10/03)
A novel series of potent, peripherally selective, and long-acting inhibitors of catechol-O-methyltransferase (COMT) has been synthesized. The introduction and nature of heteroatom-containing substituents to the side-chain of the nitrocatechol pharmacophor
