383187-82-4

Basic information

• Product Name: N-{(1S,2S,3R)-1-[(alpha-D-galactopyranosyloxy)methyl]-2,3-dihydroxyoctyl}tetracosanamide
• Synonyms: N-[(2S,3S,4R)-1-(alpha-D-galactopyranosyloxy)-3,4-dihydroxynonan-2-yl]tetracosanamide; tetracosanamide, N-[(1S,2S,3R)-1-[(alpha-D-galactopyranosyloxy)methyl]-2,3-dihydroxyoctyl]-
• CAS NO: 383187-82-4
• Molecular Formula: C₃₉H₇₇NO₉
• Molecular Weight: 704.03
• Mol File: 383187-82-4.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 861.8°C at 760 mmHg
• Flash Point: 475°C
• Density: 1.08g/cm³
• Vapor Pressure: 1.27E-34mmHg at 25°C
• Refractive Index: 1.518
• CAS DataBase Reference: N-{(1S,2S,3R)-1-[(alpha-D-galactopyranosyloxy)methyl]-2,3-dihydroxyoctyl}tetracosanamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-{(1S,2S,3R)-1-[(alpha-D-galactopyranosyloxy)methyl]-2,3-dihydroxyoctyl}tetracosanamide(383187-82-4)
• EPA Substance Registry System: N-{(1S,2S,3R)-1-[(alpha-D-galactopyranosyloxy)methyl]-2,3-dihydroxyoctyl}tetracosanamide(383187-82-4)

Safety Data

• Hazardous Substances Data: 383187-82-4(Hazardous Substances Data)

Usage

Uses

OCH is a sphingosine truncated analog of α-GalCer, stimulates natural killer T (NKT) cells to produce Th2 cytokines preventing diabetes and rheumatoid arthritis.

Definition

ChEBI: A glycophytoceramide comprising (2S,3S,4R)-2-aminononane-1,3,4-triol having an alpha-D-galctopyranosyl residue at the O-1 position and an tetracosanoyl group attached to t e nitrogen.

Upstream product

• 947747-28-6 C₈₁H₁₀₉NO₉ 
• 488-82-4 D-Arabitol 
• 557-59-5 n-tetracosanoic acid 
• 164576-09-4 4,5-anhydro-1,3-O-benzylidene-D-arabinitol 
• 164576-08-3 1,3-O-benzylidene-5-O-toluenesulfonyl-D-arabitol 
• 791611-42-2 Acetic acid (2R,3S,4S,5R,6S)-3-acetoxy-2-acetoxymethyl-5-benzyloxy-6-((2S,3S,4R)-3,4-diacetoxy-2-tetracosanoylamino-nonyloxy)-tetrahydro-pyran-4-yl ester 
• 791611-36-4 Acetic acid (1S,2R)-2-acetoxy-1-((S)-2-hydroxy-1-tetracosanoylamino-ethyl)-heptyl ester 
• 745041-79-6 (2S,3S,4R)-3,4-O-isopropylidene-1-O-(2,3,4,6-tetra-O-benzyl-α-D-galactopyranosyl)-2-tetracosanoylamino-1,3,4-nonanetriol 
• 745041-64-9 (2S,3S,4R)-2-azido-3,4-O-isopropylidene-1-O-(2,3,4,6-tetra-O-benzyl-α-D-galactopyranosyl)-1,3,4-nonanetriol 
• 745041-72-9 (2S,3S,4R)-2-amino-3,4-O-isopropylidene-1-O-(2,3,4,6-tetra-O-benzyl-α-D-galactopyranosyl)-1,3,4-nonanetriol 
• 745041-30-9 (2R,3S,4R)-1,3-O-benzylidene-2-O-methanesulfonyl-1,2,3,4-nonanetetrol 
• 745041-21-8 (2R,3S,4R)-1,3-O-benzylidene-1,2,3,4-nonanetetrol 
• 570414-15-2 (2R,3R,4R)-2-O-methanesulfonyl-1,2,3,4-nonanetetrol 
• 570414-16-3 (2S,3S,4R)-2-azido-nonane-1,3,4-triol 

Relevant articles and documents

RCAI-17, 22, 24-26, 29, 31, 34-36, 38-40, and 88, the analogs of KRN7000 with a sulfonamide linkage: Their synthesis and bioactivity for mouse natural killer T cells to produce Th2-biased cytokines

RCAI-17, 22, 24-26, 29, 31, 34-36, 38-40, and 88, the analogs of KRN7000 (1) with a sulfonamide linkage instead of an amide bond, were synthesized to examine their bioactivity for mouse natural killer (NK) T cells. RCAI-17, 22, 24-26, 29, 31, 34-36, and 8

GLYCOLIPID DERIVATIVES, PROCESS FOR PRODUCTION OF THE SAME, INTERMEDIATES FOR SYNTHESIS THEREOF, AND PROCESS FOR PRODUCTION OF THE INTERMEDIATES

Novel glycolipid derivatives, where the substituent of the sphingosine base part is a short carbon chain alkyl group, substituted or unsubstituted cycloalkyl group, substituted or unsubstituted aryl group or substituted or unsubstituted aralkyl group and

Synthesis of α-galactosyl ceramide and the related glycolipids for evaluation of their activities on mouse splenocytes

Phytosphingosine and its short-chain analog were efficiently synthesized with 19% overall yield in 10 steps, respectively, starting from an inexpensive d-lyxose. Galactosyl donors of sulfide and phosphite types bearing benzoyl protecting groups of 4- and