383381-23-5

Basic information

• Product Name: 2-[(4-isopropoxybenzoyl)amino]-4,5-dimethyl-3-thiophenecarboxamide
• Synonyms: 2-[(4-isopropoxybenzoyl)amino]-4,5-dimethyl-3-thiophenecarboxamide
• CAS NO: 383381-23-5
• Molecular Formula: C17H20N2O3S
• Molecular Weight: 332.4173
• Mol File: 383381-23-5.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-[(4-isopropoxybenzoyl)amino]-4,5-dimethyl-3-thiophenecarboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(4-isopropoxybenzoyl)amino]-4,5-dimethyl-3-thiophenecarboxamide(383381-23-5)
• EPA Substance Registry System: 2-[(4-isopropoxybenzoyl)amino]-4,5-dimethyl-3-thiophenecarboxamide(383381-23-5)

Safety Data

• Hazardous Substances Data: 383381-23-5(Hazardous Substances Data)

Relevant articles and documents

Thiophene compounds, process for preparing the same, and pharmaceutical compositions containing the same background of the invention

Compounds which are 3-aminocarbonyl-2-carboxamido-thiophene derivatives of formula (I): wherein R1and R2are, independently from each other, hydrogen, halogen or an optionally substituted group selected from aryl, straight or branched C1-C6alkyl or aryl C1-C6alkyl; or, taken together with the thiophene bond to which they are linked, R1and R2form a —(CH2)m—(NR4)n—(CH2)p— group wherein m and p are, each independently, an integer form 1 to 3, n is 0 or 1 and m+n+p is an integer from 3 to 5; and R4is hydrogen or an optionally substituted straight or branched C1-C6alkyl group; R3is a group, optionally further substituted, selected from: i) straight or branched C1-C8alkyl, C2-C6alkenyl, C2-C6alkynyl or C2-C6alkylcarbonyl; ii) aryl; iii) 3 to 7 membered carbocycle; iv) 5 to 7 membered heterocycle with from 1 to 3 heteroatoms selected from nitrogen, oxygen and sulphur; or a pharmaceutically acceptable salt thereof; are useful in the treatment of diseases associated with an altered protein kinase activity such as cancer, Alzheimer's disease, viral infections, auto-immune diseases and neurodegenerative disorders.