383401-01-2Relevant academic research and scientific papers
S-4-Methoxytrityl mercapto acids: Synthesis and application
Mourtas, Spyros,Gatos, Dimitrios,Kalaitzi, Vagiani,Katakalou, Christina,Barlos, Kleomenis
, p. 6965 - 6967 (2001)
4-Methoxytrityl (Mmt)-mercapto acids were obtained either by the reaction of mercapto acids with Mmt-chloride or by the reaction of halo acids with Mmt-thiol. The derivatives obtained were used in the solid-phase synthesis of small libraries of mercaptoacylamino acids and mercaptoacyl peptides. The removal of the Mmt-group was performed by treatment with trifluoroacetic acid (TFA) in dichloromethane (DCM) using triethylsilane (TES) as scavenger.
