383425-09-0

Basic information

• Product Name: H-Pip-NMe₂·HCl
• CAS NO: 383425-09-0
• Molecular Weight: 192.689
• Mol File: 383425-09-0.mol

Chemical Properties

• CAS DataBase Reference: H-Pip-NMe₂·HCl(CAS DataBase Reference)
• NIST Chemistry Reference: H-Pip-NMe₂·HCl(383425-09-0)
• EPA Substance Registry System: H-Pip-NMe₂·HCl(383425-09-0)

Safety Data

• Hazardous Substances Data: 383425-09-0(Hazardous Substances Data)

Upstream product

• 26250-84-0 (S)-(-)-1-(tert-butoxycarbonyl)-2-piperidinecarboxylic acid 
• 383425-10-3 tert-butyl (S)-2-(dimethylcarbamoyl)piperidine-1-carboxylate 

Relevant articles and documents

A General Strategy to Enhance Donor-Acceptor Molecules Using Solvent-Excluding Substituents

While organic donor-acceptor (D-A) molecules are widely employed in multiple areas, the application of more D-A molecules could be limited because of an inherent polarity sensitivity that inhibits photochemical processes. Presented here is a facile chemical modification to attenuate solvent-dependent mechanisms of excited-state quenching through addition of a β-carbonyl-based polar substituent. The results reveal a mechanism wherein the β-carbonyl substituent creates a structural buffer between the donor and the surrounding solvent. Through computational and experimental analyses, it is demonstrated that the β-carbonyl simultaneously attenuates two distinct solvent-dependent quenching mechanisms. Using the β-carbonyl substituent, improvements in the photophysical properties of commonly used D-A fluorophores and their enhanced performance in biological imaging are shown.

Substituted Oxindole Derivatives, Medicaments Containing Said Derivatives and Use Thereof

The invention relates to novel oxindole derivatives of general formula (I), wherein substituents A, B, X and Y are defined as in claim 1, medicaments containing said derivatives, and the use thereof in the prophylaxis and/or treatment of vasopressin-dependent and/or oxytocin-dependent diseases.

2-AMIDO-4-ISOXAZOLYL THIAZOLE COMPOUNDS EXHIBITING ATP-UTILIZING ENZYME INHIBITORY ACTIVITY, AND COMPOSITIONS, AND USES THEREOF

2-Amido-4-isoxazolyl thiazole compounds exhibiting ATP-utilizing enzyme inhibitory activity, methods of using compounds exhibiting ATP-utilizing enzyme inhibitory activity, and compositions comprising compounds exhibiting ATP-utilizing enzyme inhibitory activity, are disclosed.