38343-57-6

Basic information

• Product Name: (His(1-Me)2)-LHRH
• Synonyms: Pyr-His(1-Me)-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2
• CAS NO: 38343-57-6
• Molecular Formula: C56H77N17O13
• Molecular Weight: 1196.31668
• Mol File: 38343-57-6.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (His(1-Me)2)-LHRH(CAS DataBase Reference)
• NIST Chemistry Reference: (His(1-Me)2)-LHRH(38343-57-6)
• EPA Substance Registry System: (His(1-Me)2)-LHRH(38343-57-6)

Safety Data

• Hazardous Substances Data: 38343-57-6(Hazardous Substances Data)

Usage

Description

(His(1-Me)2)-LHRH, also known as a synthetic gonadotropin-releasing hormone analogue, is a modified peptide hormone designed to mimic the natural hormone produced in the hypothalamus. This chemical modification involves the incorporation of a methyl group at the first position of the histidine residue within the peptide chain. It is characterized by its ability to stimulate the release of luteinizing hormone and follicle-stimulating hormone from the pituitary gland, thereby regulating the production of sex hormones such as estrogen and testosterone.

Uses

Used in Hormone Regulation:
(His(1-Me)2)-LHRH is used as a hormone regulator for its ability to stimulate the release of luteinizing hormone and follicle-stimulating hormone from the pituitary gland. This regulation of hormone production is crucial for maintaining proper hormonal balance in the body.
Used in Pharmaceutical Research:
In the pharmaceutical industry, (His(1-Me)2)-LHRH is used as a research tool for studying the effects of hormone regulation on various physiological processes. Its ability to modulate hormone levels makes it a valuable asset in understanding the complex interactions between hormones and their target tissues.
Used in Treatment of Hormone-Dependent Diseases:
(His(1-Me)2)-LHRH is used as a therapeutic agent for the treatment of hormone-dependent diseases such as prostate cancer and breast cancer. Its ability to modulate hormone levels allows it to potentially slow down or inhibit the growth of hormone-dependent tumors.
Used in Drug Delivery Systems:
Similar to gallotannin, (His(1-Me)2)-LHRH can also be incorporated into drug delivery systems to enhance its applications and efficacy. Various organic and metallic nanoparticles can be employed as carriers for (His(1-Me)2)-LHRH delivery, aiming to improve its delivery, bioavailability, and therapeutic outcomes in the treatment of hormone-dependent diseases.