3837-57-8Relevant academic research and scientific papers
Pharmaceutical preparation
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, (2008/06/13)
Pharmaceutical preparations having an antiphlogistic action are described. The preparations contain, as active ingredient, a benzazole derivative corresponding to the general tautomeric formulae I STR1 wherein X represents a sulphur or oxygen atom and R1 represents a hydrogen atom and R2 a hydroxymethyl, formyl, lower carbalkoxy or lower acyl group or R1 and R2 together represent the group STR2 wherein R3 and R4 denote, independently of one another, a hydrogen atom or a C1 -C6 -alkyl group, or they contain a physiologically acceptable salt thereof. These pharmaceutical preparations are suitable in particular for the treatment of inflammatory conditions and for inhibiting the lipoxygenase and/or cyclooxygenase route of arachidonic acid metabolism.
SYNTHESIS AND TRANSFORMATIONS OF S- AND N-SUBSTITUTED 2-MERCAPTOBENZOTHIAZOLES
Rutavichyus, A. I.,Iokubaitite, S. P.
, p. 33 - 36 (2007/10/02)
2-Mercaptobenzothiazole reacts with alkyl halides and hydrazine hydrate in the thiol form, and with formaldehyde in the thione form.The alkylation of 2-mercaptobenzothiazolidin-3-yl-methanol has been performed with sulfoalkyl halides and with propan-1,3-s
