38371-80-1

Upstream product

• 43016-14-4 4-chloro-2'-hydroxychalcone dibromide 
• 138840-91-2 1H-4,5-dihydro-3-(4-chlorophenyl)-5-(2-hydroxyphenyl)pyrazole 
• 132971-93-8 (E)-1-(4-chlorophenyl)-3-(2-hydroxyphenyl)prop-2-en-1-one 
• 99-91-2 para-chloroacetophenone 
• 90-02-8 salicylaldehyde 

Downstream Products

• 108290-21-7 2-(4-chlorophenyl)pyrazolo<1,5-c><1,3>benzoxazin-5-one 

Relevant academic research and scientific papers

Synthesis of pyrazole and isoxazole in triethanolamine medium

Reactions of 2′-hydroxy chalcone dibromides 2a-1 with phenyl hydrazine and hydrazine hydrate afford pyrazoles 1a-1 and with hydroxylamine hydrochloride give isoxazoles 5a-f in triethanolamine medium. Similarly reaction of β-diketone 3b-e with phenyl hydra

PIRAZOLE MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS

The present invention relates to pyrazoles of formula (I) which are modulators of ATP-Binding Cassette ("ABC") transporters or fragments thereof, including Cystic Fibrosis Transmembrane Regulator ("CFTR"), compositions thereof, and methods therewith. The

Structure-activity relationship studies of novel pyrazolo[1,5-c][1,3]benzoxazines: Synthesis and benzodiazepine receptor affinity

Some 2-arylpyrazolo[1,5-c][1,3]benzoxazin-5-ones 1 and 5 oxopyrazolo[1,5-c][1,3]benzoxazin-2-carboxylates 2 were prepared and biologically evaluated for their binding at benzodiazepine receptor (BZR) in rat cortical membranes. Structure-activity relations