383883-66-7Relevant academic research and scientific papers
Novel N1-C4 β-lactam bond breakage. Synthesis of enantiopure γ-alkoxy-γ-keto acid derivatives
Alcaide, Benito,Almendros, Pedro,Redondo, Maria C.
, p. 1765 - 1767 (2007/10/03)
Matrix presented. Addition reaction of 2-(trimethylsilyl)thiazole (TMST) to cis- or trans-4-formyl-β-lactams gave enantiopure α-alkoxy-γ- keto acid derivatives via a novel N1-C4 bond breakage of the β-lactam nucleus. This is the first time that the cleava
