3840-02-6Relevant academic research and scientific papers
DMF Dimethyl Acetal as Carbon Source for α-Methylation of Ketones: A Hydrogenation-Hydrogenolysis Strategy of Enaminones
Borah, Ashwini,Goswami, Limi,Neog, Kashmiri,Gogoi, Pranjal
, p. 4722 - 4728 (2015/05/13)
A novel heterogeneous catalytic hydrogenation-hydrogenolysis strategy has been developed for the α-methylation of ketones via enaminones using DMF dimethyl acetal as carbon source. This strategy provides a very convenient route to α-methylated ketones using a variety of ketones without any base or oxidant. (Chemical Equation Presented).
Palladium(II)-catalyzed decarboxylative heck arylations of acyclic electron-rich olefins with internal selectivity
Fardost, Ashkan,Lindh, Jonas,Sjoeberg, Per J. R.,Larhed, Mats
supporting information, p. 870 - 878 (2014/04/03)
Despite the recent emergence of decarboxylative C-C bond forming reactions, methodologies providing internally arylated electron-rich olefins are still lacking. We herein report on palladium(II)-catalyzed decarboxylative Heck arylations of linear electron-rich olefins with excellent selectivity for the internal position. The method allows a variety of electron-rich linear olefins to undergo arylation with ortho-functionalized aromatic carboxylic acids, including heterocycles. The reaction mechanism has been explored with ESI-MS studies to confirm previous findings, and to reveal the formation of a highly stable palladium complex as a result of the Heck product reacting with the catalyst.
Fluoro-sulfones
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, (2008/06/13)
Compounds of Formula I are described. They are antagonists of leukotrienes and SRS-A.
Fluoro-sulfones
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, (2008/06/13)
Compounds of Formula I STR1 the pharmaceutically acceptable salts, and the gamma-lactone form thereof are described. They are antagonists of leukotrienes and SRS-A.
