38433-24-8Relevant academic research and scientific papers
Reactions of Bridged Halosubstituted Adamantane Derivatives with Nitric Acid
Klimochkin,Leonova,Moiseev,Aleksandrov
, p. 340 - 344 (2007/10/03)
Reactions of bridged halosubstituted adamantane derivatives with nitric acid result in nitrolysis products. In the presence of acetic anhydride, the reactions proceed at nodal positions to form nitroxy derivatives, while in the case of 2,2-dichloroadamantane, the formation of a 1,4,4-trichloro-substituted derivative is observed. The nitroxylation of 2-fluoroadamantane results in the formation of predominantly products with the Z-configuration.
REACTION OF ADAMANTANONE, DIAMANTANONE, AND THEIR DERIVATIVES WITH THIONYL CHLORIDE
Janku, Josef,Burkhard, Jiri,Vodicka, Ludek
, p. 2028 - 2034 (2007/10/02)
In reaction of adamantanone, diamantanone, and their chloro or oxo derivatives with thionyl chloride the oxo group is replaced with two chlorine atoms under formation of geminal dichloro derivatives.The presence of a chlorine atom or an oxo group in both ketones reduces the reaction rate.The reaction rate decreases with decreasing distance between the substituent and the carbonyl group.Ketones with chlorine atom in α- or β-axial position do not react with thionyl chloride.The reaction is accelerated by hydrogen chloride whereas in the presence of pyridine no reaction was observed.
