384333-95-3Relevant academic research and scientific papers
C2-symmetric proline-derived tetraamine as highly effective catalyst for direct asymmetric Michael addition of ketones to chalcones
Ma, Shijun,Wu, Lulu,Liu, Ming,Wang, Yongmei
experimental part, p. 3721 - 3729 (2012/05/20)
A C2-symmetric tetraamine catalyst was developed for the asymmetric Michael addition of ketones to chalcones. The corresponding adducts 1,5-dicarbonyl compounds were obtained in good chemical yields with high levels of diastereo- and enantioselectivities (up to >99:1 dr and 93% ee) under mild conditions. By studying the ESI-MS of the intermediates, a proposed mechanism was disclosed.
Synthesis of Rh(I) and Ir(I) complexes with chiral C2-multitopic ligands: Structural and catalytic properties
Alcón,Iglesias,Sánchez,Viani
, p. 25 - 33 (2007/10/03)
Four multitopic ligands, N,N′-bis[(S)-prolyl)phenylenediamine, N,N′-bis{[(S)-pyrrolidin-2-yl]methyl}phenylenediamine, N,N′-bis[(S)-N-benzylprolyl]phenylenediamine, N,N′-bis{[(S)-N-benzyl-pyrrolidin-2-yl]methyl}phenylenediamine, were synthesised and their co-ordination properties with Rh(I) and Ir(I) studied. The complexes were prepared by the reaction of [MCl(cod)]2 with AgPF6 and further treatment with the ligand. All ligands form one to one [ML] species with the above metal ions. The structures of these complexes were elucidated by analytical and spectroscopic data (elemental analysis, mass spectroscopy, IR, 1H- and 13C-NMR). Complexes show excellent activities and enantioselectivities up to 30% for the hydrogenation of prochiral olefins under mild reaction conditions.
