384339-80-4 Usage
Uses
Used in Food Preservation Industry:
Benzoic acid, 5-hydroxy-2-mercaptois used as a food preservative to extend the shelf life of various products. Its antimicrobial properties help inhibit the growth of bacteria, yeasts, and molds, ensuring the safety and quality of food items.
Used in Skincare Products:
In the cosmetics industry, Benzoic acid, 5-hydroxy-2-mercaptois used as an antioxidant and antimicrobial agent in skincare products. It helps protect the products from microbial contamination and provides antioxidant benefits to the skin, promoting a healthy and youthful appearance.
Used in Pharmaceutical Industry:
Benzoic acid, 5-hydroxy-2-mercaptois utilized in the pharmaceutical industry for its antimicrobial and antioxidant properties. It can be incorporated into various formulations, such as creams, ointments, and tablets, to enhance their efficacy and stability.
Used as a Chemical Intermediate in Organic Synthesis:
In the field of organic synthesis, Benzoic acid, 5-hydroxy-2-mercaptoserves as a valuable chemical intermediate. Its unique structure allows for further functionalization and modification, enabling the synthesis of a wide range of organic compounds with diverse applications.
Check Digit Verification of cas no
The CAS Registry Mumber 384339-80-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,8,4,3,3 and 9 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 384339-80:
(8*3)+(7*8)+(6*4)+(5*3)+(4*3)+(3*9)+(2*8)+(1*0)=174
174 % 10 = 4
So 384339-80-4 is a valid CAS Registry Number.
384339-80-4Relevant academic research and scientific papers
Probing Mercaptobenzamides as HIV Inactivators via Nucleocapsid Protein 7
Saha, Mrinmoy,Scerba, Michael T.,Shank, Nathaniel I.,Hartman, Tracy L.,Buchholz, Caitlin A.,Buckheit, Robert W.,Durell, Stewart R.,Appella, Daniel H.
supporting information, p. 714 - 721 (2017/05/26)
Human immunodeficiency virus type 1 (HIV-1) nucleocapsid protein 7 (NCp7), a zinc finger protein, plays critical roles in viral replication and maturation and is an attractive target for drug development. However, the development of drug-like molecules that inhibit NCp7 has been a significant challenge. In this study, a series of novel 2-mercaptobenzamide prodrugs were investigated for anti-HIV activity in the context of NCp7 inactivation. The molecules were synthesized from the corresponding thiosalicylic acids, and they are all crystalline solids and stable at room temperature. Derivatives with a range of amide side chains and aromatic substituents were synthesized and screened for anti-HIV activity. Wide ranges of antiviral activity were observed, with IC50 values ranging from 1 to 100 μm depending on subtle changes to the substituents on the aromatic ring and side chain. Results from these structure–activity relationships were fit to a probable mode of intracellular activation and interaction with NCp7 to explain variations in antiviral activity. Our strategy to make a series of mercaptobenzamide prodrugs represents a general new direction to make libraries that can be screened for anti-HIV activity.
