384342-33-0Relevant academic research and scientific papers
Biomimetic Syntheses of Polyketide Aromatics from Pyrylium Salts
Griffin, David A.,Leeper, Finian J.,Staunton, James
, p. 1035 - 1042 (2007/10/02)
Following attack by nucleophiles, various methoxypyrylium compounds derived from 2H-pyran-2-ones and 4H-pyran-4-ones react either to produce a linear β-polycarbonyl derivative in which one or more carbonyl groups is derivatised in the form of an enol ether or to form a methylene-2H-pyran.The linear polycarbonyl derivatives can undergo biomimetic cyclisation to generate polyketide aromatic system; syntheses of the following benzene derivatives are described: ethyl 2,4-dimethoxy-6-methylbenzoate (29), 2,4-dimethoxy-6-methylbiphenyl (31), and 6-(2,4-dimethoxy-6-methylphenyl)- 4-methoxy-2H-pyran-2-one (34).
