384380-52-3 Usage
Description
Abacavir Carboxylate is an inactive metabolite of the HIV-1 reverse transcriptase inhibitor Abacavir. It is formed from Abacavir via reactive aldehyde intermediates that can form adducts with proteins on valine residues and is characterized by its off-white solid appearance.
Uses
Used in Pharmaceutical Industry:
Abacavir Carboxylate is used as a major metabolite for the assessment and monitoring of Abacavir's therapeutic effects in patients. As a metabolite of Abacavir, it plays a crucial role in understanding the drug's pharmacokinetics, efficacy, and safety profile in the treatment of HIV-1 infections.
Additionally, Abacavir Carboxylate can be used as an in-house impurity for the quality control and development of Abacavir-based medications, ensuring the purity and potency of the active pharmaceutical ingredient. This application is essential for maintaining the overall quality and safety of the drug in the pharmaceutical market.
Check Digit Verification of cas no
The CAS Registry Mumber 384380-52-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,8,4,3,8 and 0 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 384380-52:
(8*3)+(7*8)+(6*4)+(5*3)+(4*8)+(3*0)+(2*5)+(1*2)=163
163 % 10 = 3
So 384380-52-3 is a valid CAS Registry Number.