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Kanamycin A sulfate is an aminoglycoside antibiotic derived from the bacterium Streptomyces kanamyceticus. It is known for its broad-spectrum activity against both Gram-negative and Gram-positive bacteria, including some strains that are resistant to other antibiotics. The sulfate form of Kanamycin A enhances its solubility and stability, which is crucial for its pharmaceutical applications. It works by inhibiting bacterial protein synthesis, ultimately leading to the death of the bacteria. Kanamycin A sulfate is used to treat various infections, such as respiratory, urinary tract, and skin infections, as well as some sexually transmitted diseases. However, due to the potential for side effects like kidney and ear toxicity, its use is often limited to cases where other antibiotics are ineffective or contraindicated.

3847-27-6

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3847-27-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 3847-27-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,8,4 and 7 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 3847-27:
(6*3)+(5*8)+(4*4)+(3*7)+(2*2)+(1*7)=106
106 % 10 = 6
So 3847-27-6 is a valid CAS Registry Number.

3847-27-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name (1S,2R,3R,4S,6R)-4,6-Diamino-3-[(6-amino-6-deoxy-α-D-glucopyranos yl)oxy]-2-hydroxycyclohexyl 3-amino-3-deoxy-α-D-glucopyranoside s ulfate (1:1)

1.2 Other means of identification

Product number -
Other names kanA sulfate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:3847-27-6 SDS

3847-27-6Upstream product

3847-27-6Relevant articles and documents

The last step of kanamycin biosynthesis: Unique deamination reaction catalyzed by the α-ketoglutarate-dependent nonheme iron dioxygenase KanJ and the NADPH-dependent reductase KanK

Sucipto, Hilda,Kudo, Fumitaka,Eguchi, Tadashi

supporting information; experimental part, p. 3428 - 3431 (2012/06/30)

Mystery solved: Using heterologous expression, the activities of two enzymes exclusively belonging to the kanamycin biosynthetic pathway have been identified in vitro. A distinctive reaction mechanism (see scheme) to produce kanamycin is proposed and the previously unknown catalytic deamination activity of KanJ dioxygenase is uncovered. Copyright

Method for apparatus for a defined serumfree medical solution useful for corneal preservation

-

, (2008/06/13)

A defined serumfree medical solution for applications in Ophthalmology, that contains one or more cell nutrient supplements which maintains and enhances the preservation of eye tissues, including human corneal tissues at low temperatures (2° C. to 15° C.). This solution is composed of a defined aqueous nutrient and electrolyte solution, supplemented with a glycosaminoglycan(s), a deturgescent agent(s), an energy source(s), a buffer system(s), an antioxidant(s), membrane stabilizing components, antibiotic(s), ATP precursors and nutrient cell supplements.

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