384799-32-0

Basic information

• Product Name: 3-[(2-fluorophenyl)methoxy]-8-methoxybenzo[c]chromen-6-one
• Synonyms: 3-[(2-fluorophenyl)methoxy]-8-methoxybenzo[c]chromen-6-one
• CAS NO: 384799-32-0
• Molecular Formula: C21H15FO4
• Molecular Weight: 350.3398032
• Mol File: 384799-32-0.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-[(2-fluorophenyl)methoxy]-8-methoxybenzo[c]chromen-6-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[(2-fluorophenyl)methoxy]-8-methoxybenzo[c]chromen-6-one(384799-32-0)
• EPA Substance Registry System: 3-[(2-fluorophenyl)methoxy]-8-methoxybenzo[c]chromen-6-one(384799-32-0)

Safety Data

• Hazardous Substances Data: 384799-32-0(Hazardous Substances Data)

Upstream product

• 1256355-40-4 4-methoxy-2-(methoxycarbonyl)phenylboronic acid 
• 6626-15-9 4-Bromoresorcinol 
• 22921-68-2 2-bromo-5-methoxy-benzoic acid 
• 108-46-3 recorcinol 
• 446-48-0 o-fluorobenzyl bromide 
• 35233-17-1 3-hydroxy-8-methoxy-6H-dibenzo-[b,d]pyran-6-one 

Relevant articles and documents

Design, synthesis, and biological evaluation of novel 6h-benzo[c]chromen-6-one derivatives as potential phosphodiesterase ii inhibitors

Urolithins (hydroxylated 6H-benzo[c]chromen-6-ones) are the main bioavailable metabolites of ellagic acid (EA), which was shown to be a cognitive enhancer in the treatment of neurodegenerative diseases. As part of this research, a series of alkoxylated 6H-benzo[c]chromen-6-one derivatives were designed and synthesized. Furthermore, their biological activities were evaluated as potential PDE2 inhibitors, and the alkoxylated 6H-benzo[c]chromen-6-one derivative 1f was found to have the optimal inhibitory potential (IC50: 3.67 ± 0.47 μM). It also exhibited comparable activity in comparison to that of BAY 60-7550 in vitro cell level studies.