38491-45-1Relevant articles and documents
Palladium catalyzed direct benzylation/allylation of malonates with alcohols-: In situ C-O bond activation
Cao, Xueqin,Zhang, Yugen
supporting information, p. 2638 - 2641 (2016/05/24)
High step- and atom-economy are the endlessly pursued in organic and pharmaceutical syntheses. Herein, a new method for directly coupling benzyl/allyl alcohols with malonates via a palladium catalyzed Tsuji-Trost type reaction was developed. The reaction was carried out in an organic carbonate solvent which would activate alcohols in situ, replacing the traditional pre-synthesized carbonates. The new process demonstrated high efficiency, high selectivity and high generality. A wide variety of mono-substituted and bis-substituted malonates were selectively produced under different conditions, and this method represents a more step- and atom-economical and environmentally benign synthetic protocol.
Observations on the Cleavage of the Bismuth-carbon bond in BiV Compounds: a New Arylation Reaction
Barton, Derek H. R.,Lester, David J.,Motherwell, William B.,Papoula, M. Teresa Barros
, p. 246 - 247 (2007/10/02)
Further examples of the selectivity of pentavalent triaryl-organobismuth oxidants are presented; deuterium labelling studies have established that the mechanism of oxidation of allylic alcohols by these reagents involves, to some extent, cleavage of the bismuth-aryl bond; several reactions involving the synthetically useful transfer of an aryl group from bismuth to nitrogen and to carbon are described.
