38495-86-2

Downstream Products

• 103607-25-6 Z(OMe)-Pro-Thr-OMe 
• 120285-92-9 Z(OMe)-Pro-Ser(Bzl)-NHNH-Troc 
• 120285-74-7 Z(OMe)-Asp(OBzl)-Pro-Ser(Bzl)-NHNH₂ 
• 103607-26-7 Z(OMe)-Phe-Val-Pro-Thr-OMe 
• 98748-34-6 Z(OMe)-Phe-Val-Pro-Thr-NH-NH₂ 

Relevant academic research and scientific papers

Use of 2-pyrimidine thiol carbonates as acylating agents for amino or imino containing compounds

Thiolcarbonates represented by the formula, SPC1 Wherein R1 and R2 are individually a hydrogen atom or a methyl group, and R3 is a straight chain or branched chain saturated or unsaturated alkyl group having 1 to 5 carbon atoms or is a benzyl or benzhydryl group which may be nuclear substituted, are quite useful for protecting the amino or imino groups of amines, hydrazines, amino acids and peptides with groups of the formula EQU1 The thiolcarbonates can be easily produced by reacting an alkali metal salt of 2-mercaptopyrimidine with phosgene, and reacting the resulting thiolchloroformate with an alcohol (R3 OH), or by reacting a 2-mercaptopyrimidine with a halocarbonic acid ester.