38499-07-9Relevant academic research and scientific papers
Water-soluble triarylphosphines as biomarkers for protein S -nitrosation
Bechtold, Erika,Reisz, Julie A.,Klomsiri, Chananat,Tsang, Allen W.,Wright, Marcus W.,Poole, Leslie B.,Furdui, Cristina M.,King, S. Bruce
, p. 405 - 414 (2010)
S-Nitrosothiols (RSNOs) represent an important class of post-translational modifications that preserve and amplify the actions of nitric oxide and regulate enzyme activity. Several regulatory proteins are now verified targets of cellular S-nitrosation, an
Fast reductive ligation of S-nitrosothiols
Wang, Hua,Xian, Ming
supporting information; experimental part, p. 6598 - 6601 (2009/03/12)
(Chemical Equation Presented) Nitroso knows: A process has been developed which converts unstable S-nitrosothiols into stable sulfenamide analogues (see scheme).Reductive ligation proceeds rapidly in mixed organic solvent/water systems to give high yields. By applying this reaction, an efficient strategy for detecting S-nitrosylation in proteins and other biological systems is envisioned.
