38521-66-3 Usage
Uses
Used in Oncology:
N,N-bis(2-chloroethyl)propan-1-amine is used as an anticancer agent for the treatment of lymphoma and Hodgkin's disease. It functions as an alkylating agent, attaching an alkyl group to the guanine base of DNA, which disrupts DNA replication and leads to cell death. This mechanism of action makes it effective in combating cancer cells.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, N,N-bis(2-chloroethyl)propan-1-amine is used as a key component in the development of cancer therapeutics. Its alkylating properties allow it to target and destroy cancer cells, making it a valuable asset in the fight against certain types of cancer. However, due to its highly toxic nature, it must be handled and administered with extreme caution by qualified healthcare professionals to minimize the risk of severe side effects and other complications.
Check Digit Verification of cas no
The CAS Registry Mumber 38521-66-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,8,5,2 and 1 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 38521-66:
(7*3)+(6*8)+(5*5)+(4*2)+(3*1)+(2*6)+(1*6)=123
123 % 10 = 3
So 38521-66-3 is a valid CAS Registry Number.
38521-66-3Relevant academic research and scientific papers
Synthesis and Mesogenic Properties of N-n-alkyl-N'-(4-n-Pentyloxyphenyl)-Piperazines
Zuniga, H.,Bartulin, J.,Ramirez, A.,Muller, H.,Taylor, T. R.
, p. 131 - 140 (2007/10/02)
The N-n-alkyl-N'-(4-n-pentyloxyphenyl)-piperazines (4) exhibit ordered smectic phases at temperatures below 100 deg C.For 3, 4, 5 and 6 carbons in the alkyl chain, two smectic phases are present and for 7, 8 and 9 carbons only one smectic phase is present.The ΔH values for 4, 5, 6 and 7 carbons are anomalous.From optical and X-ray data, the smectic phases are identified as probably smectic E and B phases.