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N,N-bis(2-chloroethyl)propan-1-amine, commonly known as mechlorethamine, is a highly toxic and reactive chemical compound that belongs to the class of alkylating agents. It is used in the treatment of specific types of cancer, such as lymphoma and Hodgkin's disease. Mechlorethamine acts by attaching an alkyl group to the guanine base of DNA, disrupting DNA replication and leading to cell death. As a nitrogen mustard compound, it is known for its severe side effects, including bone marrow suppression and an increased risk of other cancers. Due to its toxic nature, mechlorethamine is handled and administered under strict regulations by qualified healthcare professionals.

38521-66-3

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38521-66-3 Usage

Uses

Used in Oncology:
N,N-bis(2-chloroethyl)propan-1-amine is used as an anticancer agent for the treatment of lymphoma and Hodgkin's disease. It functions as an alkylating agent, attaching an alkyl group to the guanine base of DNA, which disrupts DNA replication and leads to cell death. This mechanism of action makes it effective in combating cancer cells.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, N,N-bis(2-chloroethyl)propan-1-amine is used as a key component in the development of cancer therapeutics. Its alkylating properties allow it to target and destroy cancer cells, making it a valuable asset in the fight against certain types of cancer. However, due to its highly toxic nature, it must be handled and administered with extreme caution by qualified healthcare professionals to minimize the risk of severe side effects and other complications.

Check Digit Verification of cas no

The CAS Registry Mumber 38521-66-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,8,5,2 and 1 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 38521-66:
(7*3)+(6*8)+(5*5)+(4*2)+(3*1)+(2*6)+(1*6)=123
123 % 10 = 3
So 38521-66-3 is a valid CAS Registry Number.

38521-66-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name N,N-bis(2-chloroethyl)propan-1-amine,hydrochloride

1.2 Other means of identification

Product number -
Other names Diethylamine,2,2'-dichloro-N-propyl-,hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:38521-66-3 SDS

38521-66-3Relevant academic research and scientific papers

Synthesis and Mesogenic Properties of N-n-alkyl-N'-(4-n-Pentyloxyphenyl)-Piperazines

Zuniga, H.,Bartulin, J.,Ramirez, A.,Muller, H.,Taylor, T. R.

, p. 131 - 140 (2007/10/02)

The N-n-alkyl-N'-(4-n-pentyloxyphenyl)-piperazines (4) exhibit ordered smectic phases at temperatures below 100 deg C.For 3, 4, 5 and 6 carbons in the alkyl chain, two smectic phases are present and for 7, 8 and 9 carbons only one smectic phase is present.The ΔH values for 4, 5, 6 and 7 carbons are anomalous.From optical and X-ray data, the smectic phases are identified as probably smectic E and B phases.

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