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38533-61-8

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38533-61-8 Usage

Chemical Properties

Light yellow Cryst

Uses

6-methoxy-3-nitropyridine-2-carbonitrile was synthesised from 2-Chloro-6-methoxy-3-nitropyridine. Reatant in the suzuki and negishi couplings reaction. Also as fine chemical intermediate.

Check Digit Verification of cas no

The CAS Registry Mumber 38533-61-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,8,5,3 and 3 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 38533-61:
(7*3)+(6*8)+(5*5)+(4*3)+(3*3)+(2*6)+(1*1)=128
128 % 10 = 8
So 38533-61-8 is a valid CAS Registry Number.
InChI:InChI=1/C6H5ClN2O3/c1-12-5-3-2-4(9(10)11)6(7)8-5/h2-3H,1H3

38533-61-8 Well-known Company Product Price

  • Brand
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  • Alfa Aesar

  • (H64076)  2-Chloro-6-methoxy-3-nitropyridine, 98%   

  • 38533-61-8

  • 25g

  • 564.0CNY

  • Detail
  • Alfa Aesar

  • (H64076)  2-Chloro-6-methoxy-3-nitropyridine, 98%   

  • 38533-61-8

  • 100g

  • 2254.0CNY

  • Detail
  • Aldrich

  • (C49909)  2-Chloro-6-methoxy-3-nitropyridine  98%

  • 38533-61-8

  • C49909-10G

  • 1,017.90CNY

  • Detail

38533-61-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Chloro-6-methoxy-3-nitropyridine

1.2 Other means of identification

Product number -
Other names 2-Chloro-6-Methoxy-3-nitropyridine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:38533-61-8 SDS

38533-61-8Relevant articles and documents

SELECTIVE INHIBITORS OF CLINICALLY IMPORTANT MUTANTS OF THE EGFR TYROSINE KINASE

-

Page/Page column 348, (2017/08/01)

The present invention provides compounds of Formula (I) or a subgeneric structure or species thereof, or a pharmaceutically acceptable salt, ester, solvate, and/or prodrug thereof, and methods and compositions for treating or ameliorating abnormal cell proliferative disorders, such as cancer, wherein A, R2, R3, R10, E1, E2, E3, Y, and Z are as defined herein.

Ortho-selectivity in the nucleophilic aromatic substitution (S NAr) reactions of 3-substituted, 2,6-dichloropyridines with alkali metal alkoxides

Yap, Jeremy L.,Hom, Kellie,Fletcher, Steven

scheme or table, p. 4172 - 4176 (2011/09/19)

3-Substituted, 2,6-dichloropyridines have featured in the syntheses of small molecule inhibitors of a wide variety of biological targets. Hence, the regioselective displacement of the chlorines is of significant interest. Through conducting an extensive solvent study, we have found that non-polar, aprotic solvents of low hydrogen bond basicities favour substitution of the chlorine ortho to the 3-substituent by alkali metal alkoxides. We present convincing evidence that coordination of the alkali metal counter-ion to the 3-substituent (nitro, ester, amide) is the origin of the ortho-selectivity to give a cyclic, six-membered transition state. Excellent ortho-selectivities (≥98:2) for secondary and tertiary alkoxides were realized with the sodium counter-ion, whereas the more reactive primary alkoxides required the harder, more Lewis acidic lithium counter-ion.

Cell adhesion inhibitors

-

, (2008/06/13)

The present invention relates to novel compounds that are useful for inhibition and prevention of cell adhesion and cell adhesion-mediated pathologies. This invention also relates to pharmaceutical formulations comprising these compounds and methods of using them for inhibition and prevention of cell adhesion and cell adhesion-mediated pathologies. The compounds and pharmaceutical compositions of this invention can be used as therapeutic or prophylactic agents. They are particularly well-suited for treatment of many inflammatory and autoimmune diseases.

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