38538-07-7Relevant academic research and scientific papers
Synthesis and herbicidal activity of 12-(aryloxyacyloxyimino)-1,15- pentadecanlactone derivatives
Meng, Xiang-Qing,Zhang, Jian-Jun,Liang, Xiao-Mei,Zhu, Wei-Juan,Dong, Yan-Hong,Wu, Xue-Min,Huang, Jia-Xing,Rui, Chang-Hui,Fan, Xian-Lin,Chen, Fu-Heng,Wang, Dao-Quan
experimental part, p. 610 - 617 (2010/03/03)
A series of novel 12-(aryloxyacyloxyimino)-1,15-pentadecanlactone derivatives (3) were synthesized, and their structures including configuration of C=N bond were confirmed by 1H NMR, elemental analysis and X-ray diffraction analysis. The bioass
Synthesis and fungicidal activity of macrolactams and macrolactones with an oxime ether side chain
Huang, Jia-Xing,Jia, Yue-Mei,Liang, Xiao-Mei,Zhu, Wei-Juan,Zhang, Jian-Jun,Dong, Yan-Hong,Yuan, Hui-Zu,Qi, Shu-Hua,Wu, Jin-Ping,Chen, Fu-Heng,Wang, Dao-Quan
experimental part, p. 10857 - 10863 (2009/11/30)
Three series of novel macrolactams and macrolactones - 12-alkoxyimino- tetradecanlactam, 12-alkoxyiminopentadecanlactam, and 12-alkoxyiminodecanlactone derivatives (7A, 7B, and 7C) - were synthesized from corresponding 12-oxomacrolactams and 12-oxomacrolactone. Their structures were confirmed by 1H NMR and elemental analysis. The Z and E isomers of 7A and 7B were separated, and their configurations were determined by 1H NMR. These compounds showed fair to excellent fungicidal activities against Rhizoctonia solani Kuehn. It is interesting that the Z and E isomers of most of the compounds have quite different fungicidal activities. The fact that the compounds have a gradual increase of fungicidal activity in the order of 7A, 7C, and 7B indicated that the macrocyclic derivatives with a hydrogen-bonding acceptor (=N-O-) and a hydrogen-bonding donor (-CONH-) on the ring, and a three methylenes distance (CH2CH2CH2) between these two functional groups, exhibited the best fungicidal activity. The bioassay also showed that 7B not only has good fungicidal activity but also may have a broad spectrum of fungicidal activities.
