2,4-dimethoxy-6-(piperazin-1-yl)pyrimidine, also known as tropisetron, is a chemical compound featuring a pyrimidine ring with two methoxy groups and a piperazine group attached to it. It functions as a serotonin 5-HT3 receptor antagonist, playing a crucial role in the management of nausea and vomiting associated with various medical conditions.
38539-75-2
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Basic information
- Product Name: 2,4-dimethoxy-6-(piperazin-1-yl)pyrimidine
- Synonyms: 2,4-dimethoxy-6-(piperazin-1-yl)pyrimidine
- CAS NO:38539-75-2
- Molecular Formula:
- Molecular Weight: 0
- EINECS: N/A
- Product Categories: N/A
- Mol File: 38539-75-2.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: N/A
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: 2,4-dimethoxy-6-(piperazin-1-yl)pyrimidine(CAS DataBase Reference)
- NIST Chemistry Reference: 2,4-dimethoxy-6-(piperazin-1-yl)pyrimidine(38539-75-2)
- EPA Substance Registry System: 2,4-dimethoxy-6-(piperazin-1-yl)pyrimidine(38539-75-2)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 38539-75-2(Hazardous Substances Data)
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38539-75-2 Usage
Uses
Used in Oncology:2,4-dimethoxy-6-(piperazin-1-yl)pyrimidine is used as an antiemetic agent in oncology for the prevention of nausea and vomiting caused by cancer chemotherapy and radiation therapy. It achieves this by blocking serotonin receptors within the gut and central nervous system, thereby reducing the signals that trigger these symptoms.
Used in Gastroenterology:
In the field of gastroenterology, 2,4-dimethoxy-6-(piperazin-1-yl)pyrimidine has been investigated for its potential use in the treatment of irritable bowel syndrome. Its mechanism of action involves the modulation of serotonin receptors, which can help alleviate the symptoms associated with this condition.
Used in Psychiatry:
2,4-dimethoxy-6-(piperazin-1-yl)pyrimidine is also being explored as an anti-depressant in psychiatry. 2,4-dimethoxy-6-(piperazin-1-yl)pyrimidine's interaction with serotonin receptors may contribute to its potential mood-enhancing effects, although further research is needed to fully understand its therapeutic applications in this area.
Check Digit Verification of cas no
The CAS Registry Mumber 38539-75-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,8,5,3 and 9 respectively; the second part has 2 digits, 7 and 5 respectively.Calculate Digit Verification of CAS Registry Number 38539-75:
(7*3)+(6*8)+(5*5)+(4*3)+(3*9)+(2*7)+(1*5)=152
152 % 10 = 2
So 38539-75-2 is a valid CAS Registry Number.
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2,4-dimethoxy-6-(piperazin-1-yl)pyrimidine
