38539-93-4

Upstream product

• 90-02-8 salicylaldehyde 
• 104-94-9 4-methoxy-aniline 

Downstream Products

• 59723-06-7 6-(4-methoxy-phenylazo)-1',3',3'-trimethyl-1',3'-dihydro-spiro[chromene-2,2'-indole] 

Relevant academic research and scientific papers

Synthesis, characterization and photoluminescence properties of graphene oxide functionalized with azo molecules

Two different azo molecules functionalized graphene oxide (GO) through an ester linkage have been synthesized for the first time. Chemical structure of the azo-GO hybrids was confirmed by Fourier transform infrared spectroscopy and UV-visible spectroscopy

Time dependent aggregation induced emission enhancement and the study of molecular packing in closely related azo-phenol BODIPY species

Fluorescent azo-phenol BODIPYs (1-3) have been obtained by the substituent (-OCH3/-CH3) directed synthesis of ortho (L1) and para (L2-L3) azo-phenol aldehydes. These display aggregation caused quenching (ACQ, 1) and aggregation induc

Three indole derived azo-azomethine dyes as effective chemosensors for F-ion and trace water detection

Three new dyes 13 derived from indol-carbohydrazide and azo-azomethine for the optical detection of F- ion have been developed. Dye 1 was found to be an effective colorimetric sensor for F- ion response with over 250 nm red-shift. Moreover, the resultant dye...HF2- complex (dye-F) could be successfully used as a secondary sensor for analyzing trace water in aprotic organic solvents especially in acetonitrile with a low limit of detection. In addition to detection of low-level water content in solution, test paper incorporated with 1-F complex or 2-F complex was well developed for naked-eye detection of water content in four organic solvents as mentioned above. Importantly, the test paper prepared by introducing 1-F complex or 2-F complex could be developed to prepare an ink-free rewritable paper by using water as the sole trigger. Furthermore, the same test paper could still work for many cycles without obvious loss in color quality.

Novel edaravone-based azo dyes: Efficient synthesis, characterization, antibacterial activity, DFT calculations and comprehensive investigation of the solvent effect on the absorption spectra

The present study deals with designing and synthesizing novel dyes using the drug combination of edaravone and azo compounds which can be used as an indicator for anions and cations. The desired product synthesis was accomplished via a two-step process involving diazotizing the aromatic amines followed by the resultant salts coupling with edaravone. The resulting dyes were obtained with high yields under mild conditions. The structures of the dyes were identified with UV-vis, FT-IR, 1H NMR and 13C NMR spectra and CHN analysis. To investigate the solvatochromism effect, the interaction of different solvents with the selected dyes was evaluated using several parameters including the dielectric constant, refractive index, hydrogen bond donating ability, hydrogen bond accepting ability and dipolarity/polarizability scale. To achieve deep understanding about the stability and geometrical characteristics of the azo-hydrazo tautomers of the synthesized dyes and their UV-visible spectra prediction, some DFT calculations were also carried out on the synthesized dyes. The antibacterial activities of some synthesized compounds were also evaluated using the disk diffusion method. The results revealed different activity of the selected synthesized dyes for antibacterial tests against selected Gram positive and Gram negative bacteria.

Synthesis, Characterization, Antibacterial, and Antifungal Activity of Novel 2-(2-hydroxy-5-((aryl)-diazenyl)phenyl)-3-(4-hydroxyphenyl)-thiazolidin-4-one

A series of novel thiazolidinones, that is, 2-(2-hydroxy-5-((aryl)-diazenyl)phenyl)-3-(4-hydroxyphenyl)-thiazolidin-4-one, have been synthesized by reaction of various Schiff bases 2-(4-hydroxyphenylimino)methyl)-4-(aryl)diazenyl)phenol with ethanolic thioglycolic acid. Schiff bases were obtained by the reactions of 4-amino phenol with 2-hydroxy-5-((aryl)diazenyl)benzaldehyde. The structures of the newly synthesized compounds were confirmed by IR,1H NMR, mass spectra, and C, H, N elemental analysis. The thiazolidinone derivatives were evaluated for their antibacterial and antifungal activity.

A metal complex azo class chiral, synthesis method and use thereof

The present invention discloses azo chiral metal coordination compounds, a synthesis method and applications thereof, and relates to a variety of azobenzene group-containing chiral Schiff base metal coordination compounds substituted with different substituents. According to the present invention, the obtained metal coordination compounds have characteristics of reversible photochromism property of the azobenzene function group, light-emitting property of the Schiff base metal coordination compound, and the chiral characteristic of the molecule, and have good application potential in the photochromism field, and the preparation method has characteristics of simple preparation conditions, easy operation, mild reaction conditions and easily available raw materials, and is suitable for popularization and application.

Facile and Mild Synthesis and Characterization of Some New Diazo Dyes on the Basis of Schiff Bases in the Presence of Nanocrystalline Magnesium Oxide as a Base Catalyst under Solvent-free Conditions

In this research, some new diazo dyes including Schiff base have been synthesized by the condensation reaction between ethylenediamine and derivatives of salicylaldehyde containing diazo functional groups in the presence of nanocrystalline magnesium oxide

Synthesis and identification of some new 2,3-disubstituted 1,3-oxazepine-4,7-dione derivatives containing azo group and 1,3,4-thiadiazole moiety

Azoaldehyde derivatives (1a-f) were prepared through coupling reactions between diazonium salts of six primary aromatic amines and alkaline solution of 2-hydroxy benzaldehyde. Compounds (1a-f) were then introduced in acid-catalyzed condensation reactions with 2-amino-5-mercapto-1,3,4-thiadiazole to obtain six new azoimines (2a-f). (2+5) Cycloaddition of (2a-f) with each maleic and phthalic anhydrides respectivily gave nine new oxazepines (3a-f) and (4b, 4d, 4e). The synthesized compounds might have some biological activity.

Development of new precursors for immobilizing dyes onto silica surfaces

A series of new precursors for immobilization of dyes onto silica surface have been synthesized and characterized. Diazobenzene-derived dyes were synthesized by coupling salicylaldehyde and a diazotized aniline derivative. Condensation of the resultant carbaldehyde functionalized dyes with 3-aminopropylsilatrane afforded diazo-azomethine functionalized compounds containing silatranyl moiety, which were characterized using spectroscopic techniques, elemental analysis and single-crystal X-ray diffraction. Substituent dependent variation in electronic properties of silatranyl dyes was studied and the capability of immobilization of silatranyl substituted dyes was tested by synthesizing silica nanoparticles coated with immobilized dye. The derivatization of silica was confirmed by spectrophotometric, thermogravimetric and microscopic studies. The functionalized silica exhibit uniformly dispersed spherical particles of 170 nm diameter with an estimated approximate 8 nm coating of dye. As the silatranyl substituted dyes can be isolated in crystalline forms, they proved to be better precursors for immobilization in terms of purity and uniform distribution onto silica surfaces. The modified silica surfaces possess binding sites for capturing copper ions.

An azo based colorimetric probe for the detection of cysteine and lysine amino acids and its real application in human blood plasma

The present work describes the rational design and synthesis of a simple azo based colorimetric chemodosimeter to selectively detect Cys and Lys in the environment of competitive different class of amino acids in HEPES buffer under physiological conditions. The probes 3a and 3b containing aldehyde functionality upon interaction with Cys and Lys afforded stable thiazolidine and aldimine derivatives and displayed a sensitive ratiometric response in the absorption spectra due to a change in the intramolecular charge transfer (ICT) process. The whole recognition process for amino acids gives rise to a rapid significant colorimetric response with readily detectable naked-eye sensitive color changes in the real biological sample. The mechanism of interaction between the probes and amino acids has been confirmed by the optical behavior, FT-IR, NMR and ESI-MS data analysis.