385394-43-4Relevant academic research and scientific papers
Capsaicin-like analogue induced selective apoptosis in A2058 melanoma cells: Design, synthesis and molecular modeling
Pereira, Gustavo José Vasco,Tavares, Maurício Temotheo,Azevedo, Ricardo Alexandre,Martins, Barbara Behr,Cunha, Micael Rodrigues,Bhardwaj, Rajesh,Cury, Yara,Zambelli, Vanessa Olzon,Barbosa, Euzébio Guimar?es,Hediger, Matthias A.,Parise-Filho, Roberto
, p. 2893 - 2904 (2019)
The use of molecules inspired by natural scaffolds has proven to be a very promising and efficient method of drug discovery. In this work, capsaicin, a natural product from Capsicum peppers with antitumor properties, was used as a prototype to obtain urea
