38542-77-7Relevant academic research and scientific papers
Synthesis of isoindolobenzazepine alkaloids based on radical reactions or Pd(0)-catalyzed reactions
Onozaki, Yu,Kurono, Nobuhito,Senboku, Hisanori,Tokuda, Masao,Orito, Kazuhiko
experimental part, p. 5486 - 5495 (2009/12/06)
(Chemical Equation Presented) Methods for synthesis of a ring system characteristic of isoindolobenzazepine alkaloids were studied. Synthesis of lennoxamine and a formal synthesis of chelenine were accomplished in a short route via radical or Pd(0)-cataly
An efficient method for the synthesis of enol ethers and enecarbamates. Total syntheses of isoindolobenzazepine alkaloids, lennoxamine and chilenine
Fuwa, Haruhiko,Sasaki, Makoto
, p. 1849 - 1853 (2008/02/10)
An efficient method for the synthesis of enol ethers and enecarbamates has been developed based on catalytic hydrosilane reduction of α-phosphonoxy enol ethers and α-phosphonoxy enecarbamates. This method has been applied to the total syntheses of two iso
A short synthesis of lennoxamine using a radical cascade
Taniguchi, Tsuyoshi,Iwasaki, Keiko,Uchiyama, Masahiko,Tamura, Osamu,Ishibashi, Hiroyuki
, p. 4389 - 4390 (2007/10/03)
(Chemical Equation Presented) A short synthesis of lennoxamine has been achieved by using a radical cascade involving aryl radical-induced 7-endo cyclization and homolytic aromatic substitution.
Total synthesis of (±)-lennoxamine and (±)-aphanorphine by intramolecular electrophilic aromatic substitution reactions of 2-amidoacroleins
Fuchs, James R.,Funk, Raymond L.
, p. 3923 - 3925 (2007/10/03)
equation presented Intramolecular electrophilic aromatic substitution reactions of 2-amidoacroleins constitute the key steps in the total syntheses of lennoxamine and aphanorphine. The aldehyde moiety of one cyclization product was transformed to a double
