385440-33-5Relevant academic research and scientific papers
The synthesis and evaluation of [2.2.1]-bicycloazahydantoins as androgen receptor antagonists
Balog, Aaron,Salvati, Mark E.,Shan, Weifang,Mathur, Arvind,Leith, Leslie W.,Wei, Donna D.,Attar, Ricardo M.,Geng, Jieping,Rizzo, Cheryl A.,Wang, Chihuei,Krystek, Stanley R.,Tokarski, John S.,Hunt, John T.,Gottardis, Marco,Weinmann, Roberto
, p. 6107 - 6111 (2007/10/03)
A novel series of [2.2.1]-bicycloazahydantoins has been designed and synthesized in an enantiospecific manner. Several of these compounds were found to act as antagonists to the androgen receptor. A novel series of [2.2.1]-azahydantoins has been designed
